CV Lattes
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Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Ana Paula Ramos holds a Bachelor's degree in Chemistry from the University of São Paulo (2005) and a Bachelor's degree in Chemistry from the University of São Paulo (2005). He completed his PhD in Chemistry (Physical Chemistry) at the University of São Paulo, working on a project involving the growth of calcium carbonate on biomimetic matrices formed by Langmuir-Blodgett thin films of phospholipids and LbL films of polyelectrolytes. During his doctoral studies (April to August 2008), he completed an internship abroad at the University of Bristol, UK, under the supervision of Dr. Fiona Meldrum. He developed a postdoctoral project at the University of São Paulo regarding the influence of different matrices (sol-gel, LB films, LbL films) on the luminescent properties of organic molecules and complexes containing lanthanides, deposited on waveguides, aiming at the development of optical sensors. Shee holds a Associate Professorship from the University of São Paulo. She was Coordinator of the Undergraduate Program in Chemistry - FFCLRP (2016-2018) and Chair of the Undergraduate Committee - FFCLRP (2018-2020). She is the current Coordinator of the Graduate Program in Chemistry - FFCLRP (2024-present) and Vice-Chair of the Research Committee - FFCLRP (2024-present). She was cited in the Stanford University ranking as one of the most influential researchers in the field of Physical Chemistry in the year 2024. She has experience in the formation and surface characterization of colloidal systems, especially nanoparticles and thin films. Her research projects involve the formation of biomimetic matrices containing biominerals, aiming at applications in osteoinductive systems. (Source: Lattes Curriculum)
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Biominerals are commonly found in nature in the form of hybrid organic-inorganic compounds, in which the organic portion is mainly composed by proteins and polyssacharides. On it is turn, the in the inorganic portion carbonates and phosphates can be found, mainly as hydroxyapatite (HAp) and silica. The process by which these exquisite minerals are formed is named biomineralization and can…
The synthesis of highly-ordered nanostructured materials that offer specific responses when submitted to an external stimulus is one of the application of nanotechnology. The ability to investigate substances at the molecular level started the search for materials with improved properties to medical applications. The use of these molecularly-controlled materials gave rise to a new researc…
Biomineralization is the processes from which minerals are formed in living organisms. This process generates complexes systems like bones, tooth, and pearls (nacre), in which organic matrices formed by macromolecules as lipids and proteins are bonded chemicaly and/or physically being responsible for the modifications in the local supersaturation of the ions which origins the nucleation a…
The process of osseointegration refers to the fixation of the metallic implant to the adjacent native tissue, being of utmost importance for clinical success in implant dentistry. This process depends on various factors, including cellular adhesion to the material's surface and the migration of ions from the bones to this interface, enabling the action of osteoblasts, the cells responsibl…
The therapeutic approach combined with regenerative and antimicrobial materials along with scaling and root planing (SRP) presents itself as a promising perspective for the treatment of periodontal disease. This project proposes a randomized, controlled, and double-blind clinical study aimed at developing and evaluating the regenerative effects of materials based on type II collagen (C-II…
Bone tissue is dynamic due to its self-regeneration capability throughout life,involving various types of cells in its renewal and maintenance of integrity. Insummary, among the main cell types, osteoblasts have the function of synthesizing theorganic matrix, while osteoclasts are responsible for the resorption of the tissuesmineral part. Many bone defects result from an imbalance between…
(Only some records are available in English at this moment)
One of the main research fields related to tissue engineer aims to obtain biomimetics materials able to stimulate cartilage regeneration using materials similar in structure and composition to this tissue, composed basically by cells called chondrocytes and extracellular matrix. These biomimetic materials must stimulate cell viability and function maintenance also with controlled rage of …
The demographic displacement of population aging and the appearance of chronic diseases can affect the regenerative capacities of tissues, including bone and cartilage tissue. These problems trigger the search for biomaterials able to support the regenerations and healing of these tissues. In this perspective, the use of strontium and flavonoids for bone and cartilagerelated therapies hav…
Design of three-dimensional hybrid and injectable templates (scaffolds) has emerged as a promisor approach to produce biomaterials for targeted applications. In this sense, the properties of the materials should be tuned to improve its therapeutic effect in the host tissue and to become a material able to easily adapt and shape to any type of bone defect. On that account, the use of bioac…
(Only some records are available in English at this moment)
The demographic displacement of population aging, and the appearance of chronic diseases can affect the regenerative capacities of bone tissue. These problems, coupled with the limitations of current clinical therapies, have triggered the search for alternative solutions based on the combination of biomaterials, cells and biomolecules, a strategy commonly termed Tissue Engineering (TE). T…
Understanding the bone formation process involves the difficult task to realize how both time and nature acted harmonically in a unique association between calcium phosphate and collagen that gave rise to one of the most remarkable biomaterials we have ever known. The bone consists of a porous hybrid organic/inorganic three-dimensional (3D) matrix, composed mainly by collagen, a variety o…
Biomineralization of hard tissues such as bone and dentin involves a complex spatio-temporal sequence of events regulated by bone-forming cells. One big question that still perdures on the understanding of this process is the origin of the mineral phase. It has been claimed since their discovery in the decade of 1960, that matrix vesicles (MVs) are the entities responsible to nucleate and…
The inorganic compounds present in living organisms are formed by a complex mechanism (biomineralization) which involves steps of nucleation and growth within a confined space. The need of design new bone replacement materials has driven several studies towards the process of bone formation. Bone is a hybrid material formed of plate-like non-stoichiometric hydroxyapatite (HAp) crystals an…
(Only some records are available in English at this moment)
| 4 / 3 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 17 / 14 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 4 / 4 | Completed scholarships abroad |
| 30 / 26 | All research grants and scholarships |
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