Abstract
Technological development of international patent in the attempt of make possible its commercial exploration. (AU)
Universidade de Mogi das Cruzes (UMC). Pró-Reitoria de Pesquisa, Pós-Graduação e Extensão e Assuntos Comunitários (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Bacharelado em Química from Universidade Estadual Paulista Júlio de Mesquita Filho (1982), master's at Nuclear Engineering from Universidade de São Paulo (1985) and doctorate at Química Inorgânica from Universidade Estadual Paulista Júlio de Mesquita Filho (1993). Has experience in Chemistry, focusing on Organical-Metalic Composites, acting on the following subjects: paladaciclos, ciclopaladados, complexos de paládio, antitumorais and compostos organometálicos. (Source: Lattes Curriculum)
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Technological development of international patent in the attempt of make possible its commercial exploration. (AU)
One of our research interest has been the synthesis and development of new antitumoral drugs derived from palladacycle compounds having the N,N-dimethyl-1-phenethylamine as cyclometallation agent. [1-4]. One of our results revealed that the palladium compound [Pd2(C2,N-S(-)dmpa)2(m-dppf)Cl2 ] was able to inhibit the Cathepsin-B activity in a reversible fashion being efficient antitumoral …
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