Julio C. Pastre was born in Brazil in 1979. He obtained his PhD in 2009 under the guidance of Professor Carlos Roque D. Correia at the University of Campinas UNICAMP. This was followed by a brief one-year spell working as a process chemist at Rhodia. He then spent three years as a postdoctoral researcher at UNICAMP with Professor Ronaldo A. Pilli and joined the group of Professor Steven V. Ley at the University of Cambridge as a Postdoctoral Research Associate. Since 2014, he is working as an Assistant Professor at UNICAMP, and his general areas of interest focuses on the development of new synthetic methods in batch and continuous flow regime for the synthesis of natural products, new materials, drugs and new drug candidates. (Source: Lattes Curriculum)
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Raw materials from renewable sources, as well as agro-industrial waste, represent an attractive source of useful chemical functionalities, which to date is still largely untapped in terms of their application in the fine chemicals industry. Our research group has already identified continuous flow processing as a fundamental technology for the valorization of such materials, so that any d…
Biofeedstocks in general and biowaste in particular represent an attractive source of useful chemical functionality, which to date is still largely untapped in terms of its application in the fine chemicals industry. Our group have identified continuous flow methods as a must use technology for the valorization of such materials. Indeed, many principles of Green Chemistry can be achieved …
The fine chemicals industry is entirely based on batch processes. Although the performance of batch reactors is well predictable, there are some limitations related to scale-up, reproducibility, safety, etc. The use of continuous processes by the fine chemicals industry is hampered mainly by financial and regulatory issues, however the high competitiveness of the industry and the pressure…
The goal of continuous microreactor technology is basically to improve or facilitate the ability to complete a task. In organic synthesis, microfluidic systems emerged as a technology aimed at improving a researcher's ability to perform chemical transformations, since the small size of the reactors provides precise control over the main reaction parameters. In the context of Green Chemist…
Micro reactors flow chemistry is a technology that has been developed both for the academic and industrial environments. Another hot area of science in the latest years has been Green Chemistry, using biomass to synthesize analogous compounds to oil-based ones and new compounds. Our goal is to use highly atom-economic catalytic reactions and as starting materials fructose and terpenes, ma…
The main goal of this project is to synthesise novel ionic liquids from renewable resources and their role in biomass conversion. This project is divided in two main proposals. The first one is based on hydrogen sulfates betaines as organocatalyst in carbohydrates dehydration. Water-soluble carbohydrates (fructose, glucose and sucrose) and polyssacharides (microcrystalline cellulose) will…
This project proposes the total synthesis of the cyclic depsipeptides kohamamides A, B and C, which belong to the kulolide super family, and are characterized for having a ²-hydroxyoctanoic acid derivate with a well defined sequence of aminoacid or hydroxyacid residues. These compounds present pharmacological potential, and some depsipeptides are currently on clinical trials. In this cont…
(Only some records are available in English at this moment)
The rise of pathogenic bacteria resistant to known antibiotics is a growing concern with potentially catastrophic consequences as recently noted by The Center for Disease Control. Antibiotic-resistant hospital acquired infections claim over 23,000 lives and cause greater than 2 million illnesses in the United States alone each year. The direct health care costs of such infections have be…
Chemical-induced "readthrough" of premature termination codons is an interesting approach to be explored by medicinal chemists for the treatment of genetic disorders caused by nonsense mutations. In an effort to develop new "readthrough" molecules, we intend to optimize pharmacodynamics and ADMET properties of previously synthesized analogs, and to design and generate new compounds based …
N-Heterocyclic carbenes (NHCs) are known for being good ligands in metal complexes, but they also are capable of acting as organocatalysts in important reactions, such as the Stetter reaction and redox esterification. In the literature, there is not much published regarding the immobilization of this kind of catalyst in heterogeneous support and, until just recently, immobilization of chi…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 5 / 3 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 11 / 9 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 22 / 18 | All research grants and scholarships |
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CV Lattes
ORCID