CV Lattes
GoogleMyCitations
ResearcherID
ORCID
Universidade Federal de São Paulo (UNIFESP). Campus São José dos Campos. Instituto de Ciência e Tecnologia (ICT) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Licenciatura em Ciências Biológicas from Universidade de São Paulo (2006), bachelor's at Ciencias Biologicas from Universidade de São Paulo (2004), master's at Imunologia from Depato. de Imunologia/Instituto de Ciências Biomédicas/USP (2007) and doctorate at Immunology from Universidade de São Paulo (2010). (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Previous studies in paracoccidioidomycosis (PCM), the most prevalent systemic mycosis in Latin America, revealed that immunity of hosts is tightly regulated by several suppressive mechanisms mediated by tolerogenic plasmacytoid dendritic cells, the enzyme 2,3 indoleamine dioxygenase (IDO1) and regulatory T cells (Treg). IDO1 was also seen to orchestrate local and systemic immunosuppressiv…
Previous studies in paracoccidioidomycosis (PCM), the most prevalent systemic mycosis in Latin America, revealed that immunity of hosts is tightly regulated by several suppressive mechanisms mediated by tolerogenic plasmacytoid dendritic cells, the enzyme 2,3 indoleamine dioxygenase (IDO1) and regulatory T cells (Treg). IDO1 was also seen to orchestrate local and systemic immunosuppressiv…
In infectious diseases, the enzyme indolemine 2,3 dioxygenase-1 (IDO1) that catalyzes the tryptophan (Trp) degradation along the kynurenines (Kyn) pathway has two main functions, the control of pathogen growth by reducing available Trp and immune regulation mediated by the Kyn-mediated expansion of regulatory T cells via Aryl hydrocarbon receptor (AhR). In pulmonary paracoccidioidomycosis…
Plasmacytoid dendritic cells (pDCs), considered critical for immunity against viruses, were recently associated with defense mechanisms against fungal infections. However, the immunomodulatory function of pDCs in pulmonary paracoccidiodomycosis (PCM), an endemic fungal infection of Latin America, has been poorly defined. Here, we investigated the role of pDCs in the pathogenesis of PCM ca…
Dendritic cells (DCs) constitute a link between the innate and adaptive immunity. According to the subclass and activation pattern they may play an important role in regulatory and protective immunological effects to the host. In paracoccidioidomycosis (PCM), the systemic mycosis with highest incidence in Latin America, the role of DCs has been poorly studied, although several lines of wo…
Granulomas are immunological structures important in the host defense against the thermally dimorphic fungus Paracoccidioides brasiliensis, the main agent causative of Paracoccidioidomycosis (PCM), a systemic chronic mycosis endemic several Latin America countries. The interaction of P. brasiliensis with host tissue initially triggers a congestive-exudative inflammatory reaction with a pr…
Previous studies in Paracoccidioidomycosis (PCM), the most prevalent systemic mycosis in Latin America, revealed that immunity of hosts is tightly regulated by several suppressive mechanisms mediated by tolerogenic plasmacytoid dendritic cells, the enzyme 2,3 Indoleamine Dioxygenase (IDO1) and regulatory T cells (Treg). IDO1 was also seen to orchestrate local and systemic immunosuppressiv…
(Only some records are available in English at this moment)
A previous study on Paracoccidioidomycosis (PCM), the most prevalent systemic mycosis in Latin America, revealed that the host immunity is strongly regulated by several suppressor mechanisms mediated by plasmocytoid dendritic cells, by the enzyme 2,3 indoleamine dioxygenase (IDO1) and regulatory T cells (Treg). The activity of IDO1 was demonstrated by orchestrating local and systemic immu…
Granulomas are immunological structures important in the host defense against the thermally dimorphic fungus Paracoccidioides brasiliensis, the main agent causative of Paracoccidioidomycosis (PCM), a systemic chronic mycosis endemic several Latin America countries. The interaction of P. brasiliensis with host tissue initially triggers a congestive-exudative inflammatory reaction with a pr…
Dendritic cells (DCs) constitute a link between the innate and adaptive immunity. According to the subclass and activation pattern they may play an important role in regulatory and protective immunological effects to the host. In paracoccidioidomycosis (PCM), the systemic mycosis with highest incidence in Latin America, the role of DCs has been poorly studied, although several lines of wo…
(Only some records are available in English at this moment)
In preliminary studies Ramirez-Ortiz et al. 2011, demonstrate that plasmacytoid dendritic cells (pDCs) phagocytose Aspergillus fumigatus conidia and spread over the surface of the hyphal morphotype. In response to hyphal stimulation, pDCs directly inhibit fungal growth and release IFN-± and TNF-±. These studies together with this project challenge the prevailing dogma regarding the specia…
| 2 / 2 | Ongoing research grants |
| 4 / 3 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 11 / 6 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 22 / 16 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 12 |
| Citations | 45 |
| Cit./Article | 3.8 |
| Data from Web of Science | |
DE ARAUJO, ELISEU FRANK; FERIOTTI, CLAUDIA; DE LIMA GALDINO, NAYANE ALVES; PREITE, NYCOLAS WILLIAN; GARCIA CALICH, VERA LUCIA; LOURES, FLAVIO VIEIRA. The IDO-Ahr axis controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection. FRONTIERS IN IMMUNOLOGY, v. 8, JUL 24 2017. Web of Science Citations: 16. (14/04783-2, 11/51258-2)
ARAUJO, ELISEU F.; LOURES, FLAVIO V.; BAZAN, SILVIA B.; FERIOTTI, CLAUDIA; PINA, ADRIANA; SCHANOSKI, ALESSANDRA S.; COSTA, TANIA A.; CALICH, VERA L. G.. Indoleamine 2,3-Dioxygenase Controls Fungal Loads and Immunity in Paracoccidioidomicosis but is More Important to Susceptible than Resistant Hosts. PLoS Neglected Tropical Diseases, v. 8, n. 11, NOV 2014. Web of Science Citations: 14. (12/01765-8)
DE BARROS, PATRICIA PIMENTEL; ROSSONI, RODNEI DENNIS; GARCIA, MAIRA TERRA; KAMINSKI, VALERIA DE LIMA; LOURES, FLAVIO VIEIRA; FUCHS, BETH BURGWYN; MYLONAKIS, ELEFTHERIOS; JUNQUEIRA, JULIANA CAMPOS. The Anti-Biofilm Efficacy of Caffeic Acid Phenethyl Ester (CAPE) In Vitro and a Murine Model of Oral Candidiasis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v. 11, AUG 2 2021. Web of Science Citations: 0. (19/10097-8, 19/05664-0, 17/02652-6)
DE ARAUJO, ELISEU FRANK; PREITE, NYCOLAS WILLIAN; VELDHOEN, MARC; LOURES, FLAVIO VIEIRA; GARCIA CALICH, VERA LUCIA. Pulmonary paracoccidioidomycosis in AhR deficient hosts is severe and associated with defective Treg and Th22 responses. SCIENTIFIC REPORTS, v. 10, n. 1, JUL 9 2020. Web of Science Citations: 3. (16/23189-0, 18/14762-3, 11/51258-2)
DE ARAUJO, ELISEU FRANK; MEDEIROS, DANIELLA HELENA; DE LIMA GALDINO, NAYANE ALVES; CONDINO-NETO, ANTONIO; GARCIA CALICH, VERA LUCIA; LOURES, FLAVIO VIEIRA. Tolerogenic Plasmacytoid Dendritic Cells Control Paracoccidioides brasiliensis Infection by Inducting Regulatory T Cells in an IDO-Dependent Manner. PLOS PATHOGENS, v. 12, n. 12, DEC 2016. Web of Science Citations: 10. (14/22630-9, 14/18668-0, 15/12328-6)
PREITE, NYCOLAS WILLIAN; FERIOTTI, CLAUDIA; DE LIMA, DHEMERSON SOUZA; DA SILVA, BRUNO BORGES; CONDINO-NETO, ANTONIO; PONTILLO, ALESSANDRA; GARCIA CALICH, VERA LUCIA; LOURES, FLAVIO VIEIRA. The syk-coupled C-Type lectin receptors Dectin-2 and Dectin-3 are involved in Paracoccidioides brasiliensis recognition by human Plasmacytoid Dendritic cells. FRONTIERS IN IMMUNOLOGY, v. 9, MAR 20 2018. Web of Science Citations: 1. (14/04783-2, 16/23189-0, 13/02396-9, 17/00711-5)
DE CASTRO, PATRICIA ALVES; COLABARDINI, ANA CRISTINA; MANFIOLLI, ADRIANA OLIVEIRA; CHIARATTO, JESSICA; SILVA, LILIAN PEREIRA; MATTOS, ELICIANE CEVOLANI; PALMISANO, GIUSEPPE; ALMEIDA, FAUSTO; PERSINOTI, GABRIELA FELIX; ANNICK RIES, LAURE NICOLAS; et al. Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance. PLOS GENETICS, v. 15, n. 12, DEC 2019. Web of Science Citations: 0. (17/07536-4, 16/21392-2, 14/06863-3, 16/12948-7, 16/07870-9, 16/22062-6, 14/04783-2, 17/19288-5)
DE ARAUJO, ELISEU F.; LOURES, FLAVIO V.; PREITE, NYCOLAS W.; FERIOTTI, CLAUDIA; GALDINO, NAYANE A. L.; COSTA, TANIA A.; CALICH, VERA L. G.. AhR Ligands Modulate the Differentiation of Innate Lymphoid Cells and T Helper Cell Subsets That Control the Severity of a Pulmonary Fungal Infection. FRONTIERS IN IMMUNOLOGY, v. 12, APR 16 2021. Web of Science Citations: 0. (16/23189-0, 18/14762-3, 11/51258-2)
RIES, LAURE N. A.; PARDESHI, LAKHANSING; DONG, ZHICLIANG; TAN, KAELING; STEENWYK, JACOB L.; COLABARDINI, ANA CRISTINA; FERREIRA FILHO, JAIRE A.; DE CASTRO, PATRICIA A.; SILVA, LILIAN P.; PREITE, NYCOLAS W.; et al. The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence. PLOS PATHOGENS, v. 16, n. 7, JUL 2020. Web of Science Citations: 0. (17/14159-2, 17/21983-3, 18/25217-6, 17/07536-4, 17/01188-4, 13/50954-0, 14/00789-6, 13/07937-8, 16/07870-9, 19/09278-8, 16/03322-7)
NUNES, BRUNO GHIROTTO; LOURES, FLAVIO VIEIRA; SIQUEIRA BUENO, HELOISA MARIA; CANGUSSU, ERICA BARONI; GOULART, ERNESTO; COATTI, GIULIANA CASTELLO; CALDINI, ELIA GARCIA; CONDINO-NETO, ANTONIO; ZATZ, MAYANA. Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice. European Journal of Human Genetics, v. 25, n. 12, p. 1388-1396, DEC 2017. Web of Science Citations: 0. (15/19435-2, 13/08028-1, 14/04783-2)
DE ARAUJO, ELISEU FRANK; MEDEIROS, DANIELLA HELENA; DE LIMA GALDINO, NAYANE ALVES; CONDINO-NETO, ANTONIO; GARCIA CALICH, VERA LUCIA; LOURES, FLAVIO VIEIRA. Tolerogenic Plasmacytoid Dendritic Cells Control Paracoccidioides brasiliensis Infection by Inducting Regulatory T Cells in an IDO-Dependent Manner. PLOS PATHOGENS, v. 12, n. 12, DEC 2016. Web of Science Citations: 10. (14/18668-0, 14/22630-9, 15/12328-6)
LOURES, FLAVIO V.; ARAUJO, ELISEU F.; FERIOTTI, CLAUDIA; BAZAN, SILVIA B.; COSTA, TANIA A.; BROWN, GORDON D.; CALICH, VERA L. G.. Dectin-1 Induces M1 Macrophages and Prominent Expansion of CD8(+)IL-17(+) Cells in Pulmonary Paracoccidioidomycosis. Journal of Infectious Diseases, v. 210, n. 5, p. 762-773, SEP 1 2014. Web of Science Citations: 29.
DE ARAUJO, ELISEU FRANK; FERIOTTI, CLAUDIA; DE LIMA GALDINO, NAYANE ALVES; PREITE, NYCOLAS WILLIAN; GARCIA CALICH, VERA LUCIA; LOURES, FLAVIO VIEIRA. The IDO-Ahr axis controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection. FRONTIERS IN IMMUNOLOGY, v. 8, JUL 24 2017. Web of Science Citations: 16. (14/04783-2, 11/51258-2)
ARAUJO, ELISEU F.; LOURES, FLAVIO V.; BAZAN, SILVIA B.; FERIOTTI, CLAUDIA; PINA, ADRIANA; SCHANOSKI, ALESSANDRA S.; COSTA, TANIA A.; CALICH, VERA L. G.. Indoleamine 2,3-Dioxygenase Controls Fungal Loads and Immunity in Paracoccidioidomicosis but is More Important to Susceptible than Resistant Hosts. PLoS Neglected Tropical Diseases, v. 8, n. 11, NOV 2014. Web of Science Citations: 14. (12/01765-8)
DE BARROS, PATRICIA PIMENTEL; ROSSONI, RODNEI DENNIS; GARCIA, MAIRA TERRA; KAMINSKI, VALERIA DE LIMA; LOURES, FLAVIO VIEIRA; FUCHS, BETH BURGWYN; MYLONAKIS, ELEFTHERIOS; JUNQUEIRA, JULIANA CAMPOS. The Anti-Biofilm Efficacy of Caffeic Acid Phenethyl Ester (CAPE) In Vitro and a Murine Model of Oral Candidiasis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v. 11, AUG 2 2021. Web of Science Citations: 0. (19/10097-8, 19/05664-0, 17/02652-6)
DE ARAUJO, ELISEU FRANK; PREITE, NYCOLAS WILLIAN; VELDHOEN, MARC; LOURES, FLAVIO VIEIRA; GARCIA CALICH, VERA LUCIA. Pulmonary paracoccidioidomycosis in AhR deficient hosts is severe and associated with defective Treg and Th22 responses. SCIENTIFIC REPORTS, v. 10, n. 1, JUL 9 2020. Web of Science Citations: 3. (16/23189-0, 18/14762-3, 11/51258-2)
(References retrieved automatically from State of São Paulo Research Institutions)
LOURES, Flávio Vieira. O receptor de reconhecimento de patógenos TLR-2 e a proteína adaptadora MYD88 apresentam um importante papel na infecção murina contra o Paracoccidioides brasiliensis. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (06/61048-7)