- Research Grants
Graduation in Pharmacy at Pontifícia Universidade Católica de Campinas (PUCC, 2005-2008). Masters (CNPq Scholarship) in Pharmacology at School of Medical Sciences - University of Campinas (FCM- UNICAMP, 2011-2013). PhD (FAPESP Scholarship) at Laboratory of Cardiovascular Pharmacology (FCM-UNICAMP-SP). Experience on Cardiovascular Pharmacology in the research line of: Resistant Hypertension; Target Organ Damage; Cardiovascular Biomarkers; Genetic Polymorphisms; and Clinical Research. Background in biochemical analysis, DNA extraction, genotyping, ELISA (Enzyme-Linked Immunosorbent Assay), and Western?blot technique. Experience in Clinical Research working as Teaching Assistant of the Principles and Practice of Clinical Research Course at Harvard T.H. Chan School of Public Health, Boston, USA, in 2016. Guest scientist at Berlin-Brandenburg Center for Regenerative Therapies (BCRT) - Charite University Hospital, Berlin, Germany, in 2017. Post Doctorate in Pharmacology - Cell Signalling Research Group - School of Life Sciences - University of Nottingham, UK (jul 2017 - dec 2018). Financial support given by the Brazilian Institution Coordination for the Improvement of Higher Education Personnel (CAPES - Drug Discovery Program). Research line: G protein-coupled receptors (GCPRs); Adenosine Receptors A2A e A2B; Beta arrestin; Chinese Hamster Ovarian (CHO) cells and Human Embryonic Kidney (HEK) cells. Experience: Cell Culture; Molecular Biology; Internalization assays (Confocal Microscopy, HiBit/NanoLuc); Binding assays (bioluminescence resonance energy transfer (BRET)); functional assays (CRE-SPAP, pERK, cAMP); Constructs production (plasmid); Transfections. Currently working as a Medical Science Liaison at Chiesi Pharmaceutical - Sao Paulo, Brazil - in the respiratory healthcare area (asthma and COPD). (Source: Lattes Curriculum)
Resistant hypertension (RH) is characterized by high blood pressure in spite of concurrent use of three antihypertensive agents of different classes, combined at optimal doses and including a diuretic. Indeed, RH includes patients with controlled blood pressure using four or more agents. Resistant hypertensive patients have an unfavorable prognostic and the morbidity and mortality occur...
(References retrieved automatically from State of São Paulo Research Institutions)
SABBATINI, Andréa Rodrigues. Efeitos dos níveis de MMP-2 e TIMP-2 e dos polimorfismos da MMP-2-1575 G/A; -1306 C/T e -735 C/T na hipertensão resistente = Effects of MMP-2 and TIMP-2 levels and -1575 G/A; -1306 C/T and -735 C/T MMP-2 polymorphisms in resistant hypertension. Tese (Doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas. (12/23419-4)