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Maria Aparecida Nagai

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Secretaria da Saúde (São Paulo - Estado). Coordenadoria de Serviços de Saúde (CSS). Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira (ICESP)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

graduate at Ciências Biológicas from Universidade de São Paulo (1980), graduate at Ciências Biológicas from Universidade de São Paulo (1979) and ph.d. at Biochemistry from Universidade de São Paulo (1987). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: breast cancer, cancer de mama, gene expression, cancer and carcinoma. (Source: Lattes Curriculum)

Research grants
Scholarships in Brazil
FAPESP support in numbers * Updated April 10, 2021
Total / Available in English
1 / 1 Ongoing research grants
16 / 9 Completed research grants
32 / 7 Completed scholarships in Brazil
1 / 0 Completed scholarships abroad
50 / 17 All research grants and scholarships

Associated processes
Most frequent collaborators in research granted by FAPESP
Contact researcher

Use this Research Supported by FAPESP (BV/FAPESP) channel only to send messages referring to FAPESP-funded scientific projects.


 

 

 

 

Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (19)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications15
Citations184
Cit./Article12.3
Data from Web of Science

DO AMARAL, JONATAS BUSSADOR; URABAYASHI, MARCEL SHINITI; MACHADO-SANTELLI, GLAUCIA MARIA. Cell death and lumen formation in spheroids of MCF-7 cells. Cell Biology International, v. 34, n. 3, p. 267-274, . Web of Science Citations: 12. (06/01026-0)

NAGAI, MARIA APARECIDA; GERHARD, RENE; SALAORNI, SIBELI; TAVARES GUERREIRO FREGNANI, JOSE HUMBERTO; NONOGAKI, SUELY; NETTO, MARIO MOURAO; SOARES, FERNANDO AUGUSTO. Down-regulation of the candidate tumor suppressor gene PAR-4 is associated with poor prognosis in breast cancer. International Journal of Oncology, v. 37, n. 1, p. 41-49, . Web of Science Citations: 27. (06/01026-0)

NAGAI, MARIA APARECIDA; GERHARD, RENE; FREGNANI, JOSE HUMBERTO T. G.; NONOGAKI, SUELY; RIERGER, REGINA BARBOSA; NETTO, MARIO MOURAO; SOARES, FERNANDO A.. Prognostic value of NDRG1 and SPARC protein expression in breast cancer patients. Breast Cancer Research and Treatment, v. 126, n. 1, p. 1-14, . Web of Science Citations: 54. (06/01026-0)

BONATTO, NAIELI; CARLINI, MARIA JOSE; DE BESSA GARCIA, SIMONE APARECIDA; NAGAI, MARIA APARECIDA. PHLDA1 (pleckstrin homology-like domain, family A, member 1) knockdown promotes migration and invasion of MCF10A breast epithelial cells. CELL ADHESION & MIGRATION, v. 12, n. 1, p. 37-46, . Web of Science Citations: 1. (15/10208-3)

SANTOS, MARIANA LOPES DOS; PALANCH, CAROLINA GONÇALVES; SALAORNI, SIBELI; SILVA, WILSON ARAUJO DA; NAGAI, MARIA APARECIDA. Transcriptome characterization of human mammary cell lines expressing different levels of ERBB2 by serial analysis of gene expression. International Journal of Oncology, v. 28, n. 6, p. 1441-1461, .

BESSA, SIMONE APARECIDA DE; SALAORNI, SIBELI; PATRÃO, DIOGO F. C.; MOURÃO NETO, MÁRIO; BRENTANI, MARIA MITZI; NAGAI, MARIA APARECIDA. JDP1 (DNAJC12/Hsp40) expression in breast cancer and its association with estrogen receptor status. International Journal of Molecular Medicine, v. 17, n. 2, p. 363-367, .

BUIM‚ M.E.; SOARES‚ F.A.; SARKIS‚ Á.S.; NAGAI‚ M.A.. The Transcripts of SFRP1‚ CEP63 and EIF4G2 Genes Are Frequently Downregulated in Transitional Cell Carcinomas of the Bladder. ONCOLOGY, v. 69, n. 6, p. 445-454, .

FREITAS, VANESSA M.; DO AMARAL, JONATAS BUSSADOR; SILVA, THAIOMARA A.; SANTOS, EMERSON S.; MANGONE, FLAVIA R.; PINHEIRO, JOAO DE JESUS; JAEGER, RUY G.; NAGAI, MARIA A.; MACHADO-SANTELLI, GLAUCIA MARIA. Decreased expression of ADAMTS-1 in human breast tumors stimulates migration and invasion. Molecular Cancer, v. 12, . Web of Science Citations: 25. (10/07699-1, 06/01026-0)

PEREIRA, MICHELLY C.; DE BESSA-GARCIA, SIMONE A.; BURIKHANOV, RAVSHAN; PAVANELLI, ANA CAROLINA; ANTUNES, LOURIVAL; RANGNEKAR, VIVEK M.; NAGAI, MARIA A.. Prostate apoptosis response-4 is involved in the apoptosis response to docetaxel in MCF-7 breast cancer cells. International Journal of Oncology, v. 43, n. 2, p. 531-538, . Web of Science Citations: 11. (10/16543-5)

DO AMARAL, JONATAS BUSSADOR; REZENDE-TEIXEIRA, PAULA; FREITAS, VANESSA MORAIS; MACHADO-SANTELLI, GLAUCIA MARIA. MCF-7 Cells as a Three-Dimensional Model for the Study of Human Breast Cancer. TISSUE ENGINEERING PART C-METHODS, v. 17, n. 11, p. 1097-1107, . Web of Science Citations: 21. (06/01026-0)

CASOLARI, DEBORA A.; PEREIRA, MICHELLY C.; DE BESSA GARCIA, SIMONE A.; NAGAI, MARIA A.. Insulin-like growth factor-1 and 17 beta-estradiol down-regulate prostate apoptosis response-4 expression in MCF-7 breast cancer cells. International Journal of Molecular Medicine, v. 28, n. 3, p. 337-342, . Web of Science Citations: 7. (06/01026-0)

MARCHIORI, A. C.; CASOLARI, D. A.; NAGAI, M. A.. Transcriptional up-regulation of PHLDA1 by 17 beta-estradiol in MCF-7 breast cancer cells. Brazilian Journal of Medical and Biological Research, v. 41, n. 7, p. 579-582, . Web of Science Citations: 10. (04/04607-8, 06/01026-0)

CARLINI, MARIA JOSE; RECOUVREUX, MARIA SOL; SIMIAN, MARINA; NAGAI, MARIA APARECIDA. Gene expression profile and cancer-associated pathways linked to progesterone receptor isoform a (PRA) predominance in transgenic mouse mammary glands. BMC CANCER, v. 18, . Web of Science Citations: 1. (14/13470-8, 15/10208-3)

DE ALCANTARA FILHO, PAULO R.; MANGONE, FLAVIA R.; PAVANELLI, ANA C.; DE BESSA GARCIA, SIMONE A.; NONOGAKI, SUELY; DE TOLEDO OSORIO, CYNTHIA A. B.; DE ANDRADE, VICTOR P.; NAGAI, MARIA A.. Gene expression profiling of triple-negative breast tumors with different expression of secreted protein acidic and cysteine rich (SPARC). BREAST CANCER MANAGEMENT, v. 7, n. 2, . Web of Science Citations: 0. (13/07035-4)

DE BESSA GARCIA, SIMONE APARECIDA; PAVANELLI, ANA CAROLINA; CRUZ E MELO, NATALIA; NAGAI, MARIA APARECIDA. Prostate apoptosis response 4 (PAR4) expression modulates WNT signaling pathways in MCF7 breast cancer cells: A possible mechanism underlying PAR4-mediated docetaxel chemosensitivity. International Journal of Molecular Medicine, v. 39, n. 4, p. 809-818, . Web of Science Citations: 5. (13/07035-4)

NAGAI, MARIA APARECIDA; RÓS, NANCY DA; MOURÃO NETO, MÁRIO; FARIA JÚNIOR, SILVIO RODRIGUES DE; BRENTANI, MARIA MITZI; HIRATA JÚNIOR, ROBERTO; NEVES, EDUARDO JORDÃO. Gene expression profiles in breast tumors regarding the presence or absence of estrogen and progesterone receptors. International Journal of Cancer, v. 111, n. 6, p. 892-899, .

GARCIA, S. A. B.; NAGAI, M. A.. Transcriptional regulation of bidirectional gene pairs by 17 beta-estradiol in MCF-7 breast cancer cells. Brazilian Journal of Medical and Biological Research, v. 44, n. 2, p. 112-122, . Web of Science Citations: 4. (06/01026-0)

DOS SANTOS, M. L.; GIMENES, K. P.; SILVA, JR., W. A.; NAGAI, M. A.. Transcriptome changes induced by docetaxel in human mammary cell lines expressing different levels of ERBB2. International Journal of Molecular Medicine, v. 23, n. 6, p. 733-743, . Web of Science Citations: 6. (06/01026-0)

MANGONE, FLAVIA R.; VALOYES, MAIRA A. V.; DO NASCIMENTO, RENAN G.; CONCEICAO, MERCIA P. F.; BASTOS, DANIEL R.; PAVANELLI, ANA C.; SOARES, IBERE C.; DE MELLO, EVANDRO S.; NONOGAKI, SUELY; OSORIO, CYNTHIA A. B.; et al. Prognostic and predictive value of Pleckstrin homology-like domain, family A family members in breast cancer. BIOMARKERS IN MEDICINE, v. 14, n. 16, p. 1539-1554, . Web of Science Citations: 0. (19/05252-4)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

FILHO, Lourival Antunes de Oliveira. Papel da expressão celular e extracelular do Par-4 na formação tumoral e sensibilidade a droga. Tese (Doutorado) -  Faculdade de Medicina.  Universidade de São Paulo (USP).  São Paulo.  (13/08110-0

CASOLARI, Débora Arcieri. Interação entre as vias de sinalização do IGF-I, do ER e da integrina 1 na regulação da transcrição do genes PHLDA1 e PAWR. Tese (Doutorado) -  Faculdade de Medicina.  Universidade de São Paulo (USP).  São Paulo.  (05/04183-6

CAMILLO, Cláudia Malheiros Coutinho. Análise da expressão deferencial de genes em linhagens celulares de carcinoma de próstata.  130 f. Tese (Doutorado) -  Faculdade de Medicina.  Universidade de São Paulo (USP).  São Paulo.  (00/00196-2

PAVANELLI, Ana Carolina. Avaliação do transcriptoma e proteoma de células de câncer de mama com diferente perfil de expressão de SPARC (secreted protein acidic and rich in cysteine) na presença e ausência de docetaxel. Dissertação (Mestrado) -  Faculdade de Medicina.  Universidade de São Paulo (USP).  São Paulo.  (12/03920-0

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