- Research Grants
graduation at Ciências Biológicas from Universidade de São Paulo (2003) and doctorate at Microbiology from Universidade de São Paulo (2010). Has experience in Genetics, focusing on Mutagenesis, acting on the following subjects: base excision repair, danos oxidativos, ensaio in vitro, doença de alzheimer and protease. (Source: Lattes Curriculum)
The population aging observed in the last century has led to a significant increase in the number of cases of Alzheimer's disease (AD) in the world, whose associated costs are becoming significant to the public health systems. Despite major recent advances in identifying genes and cellular targets involved in the pathophysiology of the disease, the molecular mechanisms that lead to the ...
Mitochondrial dysfunction appears as an early event in Alzheimer's disease (AD) pathology and in other neurodegenerative diseases. AD individuals accumulate oxidized DNA lesions in the mitochondrial genome (mtDNA) when compared to age-matched control individuals, which is believed to play a causal role in the mitochondrial dysfunction observed in the AD pathology. However, it is not cle...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
(References retrieved automatically from State of São Paulo Research Institutions)
SOLTYS, Daniela Tathiana. Análise da natureza genotípica de pacientes Xeroderma pigmentosum brasileiros.. Tese (Doutorado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (05/56296-9)