Luiz Guilherme de Siqueira Branco
CV Lattes
GoogleMyCitations
Universidade de São Paulo (USP). Faculdade de Odontologia de Ribeirão Preto (FORP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
master's at Physiology from Universidade de São Paulo (1990) and ph.d. at Physiology from Universidade de São Paulo (1993). Has experience in Physiology, focusing on General Physiology, acting on the following subjects: hipotermia, temperatura corporal, óxido nítrico, hypoxia and toad. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Serotonin inhibits sepsis-like severe systemic inflammation |
- Pathophysiological changes during systemic inflammation, AP.TEM
Abstract
The systemic inflammatory response syndrome (SIRS) is an inflammatory condition that affects the whole body and represents a serious threat. Endotoxemia, sepsis and its complications (septic shock and multiple organ failure) are the major cause of death in intensive care units worldwide, despite recent major technological advances. Lack of knowledge of the pathophysiological mechanisms ...
- Role of hydrogen sulphide (H2S) on the ventilatory responses to hypercapnia, AP.R
Abstract
Hydrogen sulfide (H2S), recently described as the third member of the group of gaseous transmitters, is produced endogenously by metabolic pathways with predominant participation of two enzymes: cystathionine beta-synthase (CBS ) and cystathionine gamma-lyase (CSE ). The presence and participation of CBS and CSE for generating H2S in response to hypoxia have been reported in the carotid...
- Role of hydrogen sulfide during septic shock hypothermia, AP.R
Abstract
Hydrogen sulfide (H2S) has been recently appointed as an important endogenous gas acting during systemic inflammation. In animal models of systemic inflammation, H2S basal levels are altered in the preoptic area of the hypothalamus (POA) in response to the administration of endotoxin (bacterial lipopolysaccharide, LPS). Furthermore, we demonstrated that H2S in POA modulates the febrile ...
- Amygdaloid circuitry in the innate fear modulation, AP.R
Abstract
Tonic immobility (IT) is a behavioral defensive innate fear triggered in situations of inescapable confrontation between predator-prey. This response is characterized by loss of righting reflex and the relative lack of responsiveness to environmental stimuli. Consistent studies have shown the involvement of different brain areas to modulate this response, including the periaqueductal gr...
(Only some records are available in English at this moment)
- Role of endogenous preoptic hydrogen sulfide modulating LPS tolerance, BP.DR
Abstract
Fever is by definition a regulated increase in body core temperature (Tb) in defense of the organism against pathogens. Immune system-pathogen interaction induces cytokines and prostaglandins release (inflammation mediators) that leads to activation of central regions involved in control of Tb, being anteroventral preoptic region (AVPO) hierarchically the most important region involved ...
- Physiopathological changes during systemic inflammation, BP.TT
- The role of the inflammatory reflex in the endotoxin tolerance, BP.IC
Abstract
Seventy years ago, the first study describing tolerance after bacteria inoculation in rabbits was published. Since that time, the importance of bacterial endotoxin tolerance has been researched in both humans and animals, protecting the organism from infectious agents. The spleen is an important modulator of systemic production of pro- and anti-inflammatory cytokines, producing pro-infl...
- Role of serotonin in the preoptic area in the modulation of body temperature and nociception during systemic inflammation, BP.DR
Abstract
Inflammation is a sign of neuroimmune interaction acting in the host defense, inducing the production of inflammatory mediators, fever and pain. These conditions are mimicked by Systemic Inflammation (SI) induced by lipopolysaccharide (LPS - outer membrane component of gram-negative bacteria). Fever results from the activation of thermoregulatory neurons in the anteroventral region of t...
(Only some records are available in English at this moment)
- The role of leptin signaling in the dorsomedial hypothalamus in the upper airway patency during sleep, BE.EP.PD
Abstract
Obstructive sleep apnea (OSA) is a severe breathing disorder, characterized by periodic obstruction of the upper airways during sleep with eventual impact in the cardiovascular and respiratory systems as well as in the inflammatory status. OSA and its critical respiratory complications may be associated with obesity hypoventilation syndrome. Previous studies have documented the role of ...
- Spinal 5-hydroxytryptamine (5-HT) receptors and activation of brown adipose tissue during systemic inflammation, BE.EP.DR
Abstract
5-hydroxytryptamine (5-HT) plays key thermoregulatory role acting in the central nervous system (CNS). 5-HT spinal administration results in hypothermia and emerging data demonstrate that activation of 5-HT receptors within the intermediolateral column (IML) of the spinal cord increases the sympathetic outflow to brown adipose tissue (BAT). In agreement, endogenous 5-HT1A and 5-HT7 rece...
- "role of estradiol in thermoregulatory behavior and hyperalgesia in ovariectomized rats", BE.EP.DR
Abstract
Sex hormones, such as estradiol, play an important role in body temperature regulation and pain sensation. Low estradiol concentrations, often seen in menopausal women, are associated with the occurrence of hot flushes, which are characterized by an intense sensation of heat, followed by profuse sweating and an increase in blood flow to the skin, which leads to reddening of the face and...
- Role endogenous of hydrogen sulphide (H2S) in the NTS on respiratory activity during hypoxia, BE.EP.PD
Abstract
Hydrogen sulfide (H2S) has recently been considered an additional endogenous gasotransmitter and within the central nervous system, H2S is predominantly produced by the enzyme cystathionine-²-synthase (CBS). CBS-produced H2S may regulate the cardiorespiratory system and modulates peripheral chemoreceptor sensory afferents that project to the nucleus tractus solitarus (NTS), as well as t...
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 21 / 12 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 48 / 15 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 5 / 4 | Completed scholarships abroad |
| 77 / 34 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 26 |
| Citations | 240 |
| Cit./Article | 9.2 |
| Data from Web of Science | |
DA SILVA, GLAUBER S. F.; GLASS, MOGENS L.; BRANCO, LUIZ G. S.. Temperature and respiratory function in ectothermic vertebrates. Journal of Thermal Biology, v. 38, n. 2, p. 55-63, FEB 2013. Web of Science Citations: 14.
DONATTI, ALBERTO F.; SORIANO, RENATO N.; SABINO, JOAO P.; BRANCO, LUIZ G. S.. Involvement of endogenous hydrogen sulfide (H2S) in the rostral ventrolateral medulla (RVLM) in hypoxia-induced hypothermia. Brain Research Bulletin, v. 108, p. 94-99, SEP 2014. Web of Science Citations: 6.
KWIATKOSKI, M.; SORIANO, R. N.; DA SILVA, G. S. F.; FRANCESCATO, H. D.; COIMBRA, T. M.; GLASS, M. L.; CARNIO, E. C.; BRANCO, L. G. S.. Endogenous preoptic hydrogen sulphide attenuates hypoxia- induced hyperventilation. ACTA PHYSIOLOGICA, v. 210, n. 4, p. 913-927, APR 2014. Web of Science Citations: 12.
DONATTI, ALBERTO F.; ARAUJO, REBECA M.; SORIANO, RENATO N.; AZEVEDO, LEOPOLDO U.; LEITE-PANISSI, CHRISTIE A.; BRANCO, LUIZ G. S.. Role of hydrogen sulfide in the formalin-induced orofacial pain in rats. European Journal of Pharmacology, v. 738, p. 49-56, SEP 5 2014. Web of Science Citations: 14.
DONATTI, ALBERTO F.; SORIANO, RENATO N.; SABINO, JOAO P.; BRANCO, LUIZ G. S.. Endogenous hydrogen sulfide in the rostral ventrolateral medulla/Botzinger complex downregulates ventilatory responses to hypoxia. Respiratory Physiology & Neurobiology, v. 200, p. 97-104, AUG 15 2014. Web of Science Citations: 7.
FABRIS‚ G.; STEINER‚ A.A.; ANSELMO-FRANCI‚ J.A.; BRANCO‚ L.G.S.. Role of nitric oxide in rat locus coeruleus in hypoxia-induced hyperventilation and hypothermia. Neuroreport, v. 11, n. 13, p. 2991-2995, 2000.
DONATTI, ALBERTO FERREIRA; ANDRADE LEITE-PANISSI, CHRISTIE RAMOS. GABAergic antagonist blocks the reduction of tonic immobility behavior induced by activation of 5-HT2 receptors in the basolateral nucleus of the amygdala in guinea pigs. Brain Research Bulletin, v. 79, n. 6, p. 358-364, AUG 14 2009. Web of Science Citations: 11.
DONATTI, ALBERTO FERREIRA; SORIANO, RENATO NERY; ANDRADE LEITE-PANISSI, CHRISTIE RAMOS; BRANCO, LUIZ G. S.; DE SOUZA, ALBERT SCHIAVETO. Anxiolytic-like effect of hydrogen sulfide (H2S) in rats exposed and re-exposed to the elevated plus-maze and open field tests. Neuroscience Letters, v. 642, p. 77-85, MAR 6 2017. Web of Science Citations: 5.
NOGUEIRA, JONATAS E.; SORIANO, RENATO N.; FERNANDEZ, RODRIGO A. R.; FRANCESCATO, HELOISA D. C.; SAIA, RAFAEL S.; COIMBRA, TEREZILA M.; ANTUNES-RODRIGUES, JOSE; BRANCO, LUIZ G. S.. Effect of Physical Exercise on the Febrigenic Signaling is Modulated by Preoptic Hydrogen Sulfide Production. PLoS One, v. 12, n. 1, JAN 24 2017. Web of Science Citations: 5.
P.M. DE PAULA; L.G.S. BRANCO. Glutamatergic neurotransmission modulates hypoxia-induced hyperventilation but not anapyrexia. Brazilian Journal of Medical and Biological Research, v. 37, n. 10, p. 1581-1589, Out. 2004.
SANTOS, BRUNA M.; COSTA, LUIS H. A.; ROCHA, MARIA J.; BRANCO, LUIZ G. S.. Central leukotrienes modulate fever tolerance to LPS in rats. Journal of Thermal Biology, v. 84, p. 245-249, AUG 2019. Web of Science Citations: 0.
EMILIO-SILVA, MAYCON T.; MOTA, CLARISSA M. D.; HIRUMA-LIMA, CLELIA A.; ANTUNES-RODRIGUES, JOSE; CARNIO, EVELIN C.; BRANCO, LUIZ G. S.. Antipyretic Effects of Citral and Possible Mechanisms of Action. Inflammation, v. 40, n. 5, p. 1735-1741, OCT 2017. Web of Science Citations: 3.
SARAMAGO, EDUARDO A.; BORGES, GABRIELA S.; SINGOLANI-, JR., CARLITOS G.; NOGUEIRA, JONATAS E.; SORIANO, RENATO N.; CARNIO, EVELIN C.; BRANCO, LUIZ G. S.. Molecular hydrogen potentiates hypothermia and prevents hypotension and fever in LPS-induced systemic inflammation. BRAIN BEHAVIOR AND IMMUNITY, v. 75, p. 119-128, JAN 2019. Web of Science Citations: 4.
SABINO, JOAO PAULO J.; SORIANO, RENATO N.; SANTOS, BRUNA M.; DONATTI, ALBERTO F.; FERNANDEZ, RODRIGO R.; DA SILVA, GLAUBER S. F.; BRANCO, LUIZ G. S.. Central administration of aminooxyacetate, an inhibitor of H2S production, affects thermoregulatory but not cardiovascular and ventilatory responses to hypercapnia in spontaneously hypertensive rats. Respiratory Physiology & Neurobiology, v. 263, p. 38-46, MAY 2019. Web of Science Citations: 0.
DE PAULA, BRUNA B.; DE MELO, JEANNE R.; LEITE-PANISSI, CHRISTIE R. A.. Modulation of tonic immobility by GABAA and GABAB receptors of the medial amygdala. Neuroscience Letters, v. 699, p. 189-194, APR 23 2019. Web of Science Citations: 0.
MOTA, CLARISSA M. D.; ANTUNES-RODRIGUES, JOSE; BRANCO, LUIZ G. S.. Central fractalkine stimulates central prostaglandin E-2 production and induces systemic inflammatory responses. Brain Research Bulletin, v. 140, p. 311-317, JUN 2018. Web of Science Citations: 0.
ALMEIDA, M. CAMILA; HEW-BUTLER, TAMARA; SORIANO, RENATO N.; RAO, SARA; WANG, WEIYA; WANG, JUDY; TAMAYO, NURIA; OLIVEIRA, DANIELA L.; NUCCI, TATIANE B.; ARYAL, PRAFULLA; et al. Pharmacological Blockade of the Cold Receptor TRPM8 Attenuates Autonomic and Behavioral Cold Defenses and Decreases Deep Body Temperature. JOURNAL OF NEUROSCIENCE, v. 32, n. 6, p. 2086-2099, FEB 8 2012. Web of Science Citations: 120.
AMORIM, MATEUS R.; DE DEUS, JUNIA L.; CAZUZA, RAFAEL A.; MOTA, CLARISSA M. D.; DA SILVA, LUIZ E. V.; BORGES, GABRIELA S.; BATALHAO, MARCELO E.; CARNIO, EVELIN C.; BRANCO, LUIZ G. S.. Neuroinflammation in the NTS is associated with changes in cardiovascular reflexes during systemic inflammation. JOURNAL OF NEUROINFLAMMATION, v. 16, JUN 20 2019. Web of Science Citations: 0.
NOGUEIRA, JONATAS E.; AGOSTINHO, BRENDA K. L.; MOTA, CLARISSA M. D.; BRANCO, LUIZ G. S.. Splenic anti-inflammatory reflex in immune tolerance. Journal of Thermal Biology, v. 85, OCT 2019. Web of Science Citations: 0.
DONATTI, ALBERTO FERREIRA; SORIANO, RENATO NERY; ANDRADE LEITE-PANISSI, CHRISTIE RAMOS; BRANCO, LUIZ G. S.; DE SOUZA, ALBERT SCHIAVETO. Anxiolytic-like effect of hydrogen sulfide (H2S) in rats exposed and re-exposed to the elevated plus-maze and open field tests. Neuroscience Letters, v. 642, p. 77-85, MAR 6 2017. Web of Science Citations: 5.
AMORIM, MATEUS R.; DE DEUS, JUNIA L.; CAZUZA, RAFAEL A.; MOTA, CLARISSA M. D.; DA SILVA, LUIZ E. V.; BORGES, GABRIELA S.; BATALHAO, MARCELO E.; CARNIO, EVELIN C.; BRANCO, LUIZ G. S.. Neuroinflammation in the NTS is associated with changes in cardiovascular reflexes during systemic inflammation. JOURNAL OF NEUROINFLAMMATION, v. 16, JUN 20 2019. Web of Science Citations: 0.
MOTA, CLARISSA M. D.; BORGES, GABRIELA S.; AMORIM, MATEUS R.; CAROLINO, RUITHER O. G.; BATALHAO, MARCELO E.; ANSELMO-FRANCI, JANETE A.; CARNIO, EVELIN C.; BRANCO, LUIZ G. S.. Central serotonin prevents hypotension and hypothermia and reduces plasma and spleen cytokine levels during systemic inflammation. BRAIN BEHAVIOR AND IMMUNITY, v. 80, p. 255-265, AUG 2019. Web of Science Citations: 0.
SANTOS, BRUNA M.; COSTA, LUIS H. A.; ROCHA, MARIA J.; BRANCO, LUIZ G. S.. Central leukotrienes modulate fever tolerance to LPS in rats. Journal of Thermal Biology, v. 84, p. 245-249, AUG 2019. Web of Science Citations: 0.
SARAMAGO, EDUARDO A.; BORGES, GABRIELA S.; SINGOLANI-, JR., CARLITOS G.; NOGUEIRA, JONATAS E.; SORIANO, RENATO N.; CARNIO, EVELIN C.; BRANCO, LUIZ G. S.. Molecular hydrogen potentiates hypothermia and prevents hypotension and fever in LPS-induced systemic inflammation. BRAIN BEHAVIOR AND IMMUNITY, v. 75, p. 119-128, JAN 2019. Web of Science Citations: 4.
NOGUEIRA, JONATAS E.; AGOSTINHO, BRENDA K. L.; MOTA, CLARISSA M. D.; BRANCO, LUIZ G. S.. Splenic anti-inflammatory reflex in immune tolerance. Journal of Thermal Biology, v. 85, OCT 2019. Web of Science Citations: 0.
SABINO, JOAO PAULO J.; ARIZA TRASLAVINA, GUILLERMO A.; BRANCO, LUIZ G. S.. Role of central hydrogen sulfide on ventilatory and cardiovascular responses to hypoxia in spontaneous hypertensive rats. Respiratory Physiology & Neurobiology, v. 231, p. 21-27, SEP 2016. Web of Science Citations: 4.
EMILIO-SILVA, MAYCON T.; MOTA, CLARISSA M. D.; HIRUMA-LIMA, CLELIA A.; ANTUNES-RODRIGUES, JOSE; CARNIO, EVELIN C.; BRANCO, LUIZ G. S.. Antipyretic Effects of Citral and Possible Mechanisms of Action. Inflammation, v. 40, n. 5, p. 1735-1741, OCT 2017. Web of Science Citations: 3.
MOTA, CLARISSA M. D.; ANTUNES-RODRIGUES, JOSE; BRANCO, LUIZ G. S.. Central fractalkine stimulates central prostaglandin E-2 production and induces systemic inflammatory responses. Brain Research Bulletin, v. 140, p. 311-317, JUN 2018. Web of Science Citations: 0.
SABINO, JOAO PAULO J.; SORIANO, RENATO N.; SANTOS, BRUNA M.; DONATTI, ALBERTO F.; FERNANDEZ, RODRIGO R.; DA SILVA, GLAUBER S. F.; BRANCO, LUIZ G. S.. Central administration of aminooxyacetate, an inhibitor of H2S production, affects thermoregulatory but not cardiovascular and ventilatory responses to hypercapnia in spontaneously hypertensive rats. Respiratory Physiology & Neurobiology, v. 263, p. 38-46, MAY 2019. Web of Science Citations: 0.
DE PAULA, BRUNA B.; DE MELO, JEANNE R.; LEITE-PANISSI, CHRISTIE R. A.. Modulation of tonic immobility by GABAA and GABAB receptors of the medial amygdala. Neuroscience Letters, v. 699, p. 189-194, APR 23 2019. Web of Science Citations: 0.
DONATTI, ALBERTO F.; SORIANO, RENATO N.; SABINO, JOAO P.; BRANCO, LUIZ G. S.. Involvement of endogenous hydrogen sulfide (H2S) in the rostral ventrolateral medulla (RVLM) in hypoxia-induced hypothermia. Brain Research Bulletin, v. 108, p. 94-99, SEP 2014. Web of Science Citations: 6.
P.M. DE PAULA; L.G.S. BRANCO. Glutamatergic neurotransmission modulates hypoxia-induced hyperventilation but not anapyrexia. Brazilian Journal of Medical and Biological Research, v. 37, n. 10, p. 1581-1589, Out. 2004.
(References retrieved automatically from State of São Paulo Research Institutions)
TEDESCHI, Valeria Pontelli Navarro. Tolerância a endotoxina no periodonto de ratos: participação do óxido nítrico. 2009. Tese (Doutorado) – Faculdade de Odontologia de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.
DIAS, Mirela Barros. Papel do óxido nítrico na tolerância ao LPS em camundongos. 2005. 77f. Dissertação (Mestrado) - Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.
PARO, Flavia Marini. Participação do glutamato na hipotermia induzida por arginina vasopressina sistêmica em ratos. 2003. 95f. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.