CV Lattes
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ORCID
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Pharmacy and Biochemistry from the University of São Paulo (1985), master's (1990) and doctorate (1996) in Pharmacology from the University of São Paulo. Since 2014, is Associate Professor in the Department of Clinical Analysis and Toxicological of the School of Pharmaceutical Sciences, University of São Paulo. Has experience in the area of neurodegeneration, such as Alzheimer's disease, oxidative stress. Current research area is on Toxicology, with emphasis on neurotoxicity of cigarette smoke, methylecgonidine (pyrolysis product of cocaine) and in the search for new alternatives for the treatment of substance use disorder. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| El cronómetro del cerebro |
| The brain’s timepiece |
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
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Cocaine is a psychostimulant alkaloid, being in Brazil and Europe, the second most used illicit drug, with a high potential to induce addiction. Faced with this problem, research on psychedelics has intensified with a focus on the treatment of drug addiction. Psychedelics have a good safety profile, do not induce drug addiction and have low potential to cause tolerance. The most studied p…
Epigenetic are modifications that occur in that are DNA capable of controlling thetranscriptional process. During the egg's implantation phase, DNA is more vulnerable toexternal influences such as cigarette smoke, increasing the risk of retardation of fetaldevelopment, risk of postnatal sudden death and abnormalities of the immune system.Moreover, children of mothers who smoke develop ast…
Neurotoxicity has been defined as any adverse effect on the structure and function of the nervous system. Thus, the aim of this study is to evaluate the effects of environmental tobacco smoke (ETS) in vivo and the effects of anhydroecgonine methyl ester (AEME) in vitro. The focus of the ETS part is synaptic plasticity and the endocannabinoid system. Mice C57/BL will be exposed to a mixtur…
(Only some records are available in English at this moment)
Ketamine is an anesthetic commonly used illegally by adolescents and young adults in parties and raves, due to the fact that it presents psychotropic actions which intensifies social interaction. Ethanol, on the other hand, is a legal substance and its consumption is socially accepted, which can facilitate its abusive use, as well as the association with other substances, such as ketamine…
Cocaine (COC), a drug derived from coca leaves (Erythroxylon coca) is found in two chemical forms for use: cocaine hydrochloride, known as "powder", used intranasally or intravenously, and the base form, known as Crack, used through smoke. The process of burning the crack stones generates a product called anhydroecgonine methyl ester (AEME), which is inhaled along with the volatilized coc…
At the beginning of central nervous system (CNS) development many neurotoxic agents, such as nicotine and cigarette smoke, may influence in different mechanism that characterize this stage. Considering these events, this project intend to understand better the effects of exposure to cigarette smoke during the beginning of CNS development and possible consequences in adolescence and adulth…
(Only some records are available in English at this moment)
| 13 / 9 | Completed research grants |
| 25 / 16 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 39 / 25 | All research grants and scholarships |
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