CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São José dos Campos. Instituto de Ciência e Tecnologia (ICT) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated from the School of Pharmaceutical Sciences of São Paulo State University - UNESP in 2006. Has experience in Chemistry, focusing on Natural Product Chemistry (isolation, structure elucidation and bioactivity). Developed his PhD (2012) research, in the Institute of Chemistry (IQ) at UNESP, under the supervision of Prof. Maysa Furlan. During 2009-2010 was appointed visiting research scholar in the Department of Chemistry at Syracuse University/BioTools, Inc., NY/FL USA, under the supervision of Prof. Laurence A. Nafie, working on the application of vibrational circular dichroism (VCD) to determine the absolute configuration of natural benzopyrans. Developed postdoc research at IQ-UNESP/Araraquara (2012-2015), under the supervision of Prof. Vanderlan Bolzani. During 2012-2013 was appointed visiting scientist in the Manchester Institute of Biotechnology at the University of Manchester, under the supervision of Dr Ewan Blanch, working with Rman Optical Activity (ROA) for configurational studies of natural products. Held an early-career investigator position funded by FAPESP in the Department of Chemistry at Federal University of São Carlos - UFSCar (2015-2018). Currently works as an assistant professor of chemistry at Federal University of São Paulo - UNIFESP, in Sao Jose dos Campos, SP, Brazil, where leads a research group focused on vibrational optical activity (VOA). (Source: Lattes Curriculum)
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Natural product chemistry deals with organic molecules of high structural and stereochemical complexity of different classes and biosynthetic origins. The main techniques used in structural elucidation/determination, mass spectrometry (MS) and magnetic nuclear resonance (NMR), are intrinsically insensitive to chirality, limiting their application in absolute stereochemistry studies. Hist…
Chirality is ubiquitous in nature and is a cornerstone of life itself. On a molecular level it is reflected in the fascinating structural complexity of many secondary metabolites. Over the years, nature-derived and/or inspired compounds have been playing a major role in drug discovery and development processes, as they are intrinsically endowed with the structural and stereochemical requi…
(Only some records are available in English at this moment)
Furofuran lignans are important bioactive secondary metabolites widely distributed in the plant kingdom. Even though their biosynthesis is described from the enantioselective dimerization of two phenylpropanoid units, varying enantiomeric compositions have been reported in different plant species. Additionally, their absolute configuration assignments are mostly based on empirical compari…
The exact orientation of the atoms of a given molecule in space, i.e. the absolute configuration (AC) has been a complex and intriguing problem to be solved. This feature is especially critical for bioactive natural products, which are predominantly chiral. Although there are several methods capable of determining AC of chiral compounds, many present requirements that may limit their appl…
Chiral molecules are characterized by three-dimensional handedness and can exist in two enantiomeric forms of opposite absolute configuration (AC). Most natural products and biologically active compounds are chiral and their biological and molecular functions are closely related to their chirality, that is, AC and conformation. Therefore, the unambiguous determination of the AC and confor…
| 1 / 1 | Ongoing grants |
| 4 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 5 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 12 / 10 | All research grants and scholarships |
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