He holds a degree in Pharmacy and Biochemistry from the Pontifical Catholic University of Rio Grande do Sul (2002), a master's degree (2005) and a doctorate (2007) in Pharmacology from the Faculty of Medicine of Ribeirão Preto, University of São Paulo and a postdoctoral degree from the Institute of Infection. , Immunity and Inflammation - University of Glasgow. He is currently Associate Professor at the Department of Pharmacology at FMRP-USP. Member of the Brazilian Society of Experimental Pharmacology and Therapeutics, of the Brazilian Society of Immunology and of the British Society for Immunology. He has experience in immunopharmacology and immunoregulation. His line of research aims to understand the cellular and molecular mechanisms that regulate inflammation and the immune response and how these can be used as therapeutic targets for the treatment of inflammatory diseases. (Source: Lattes Curriculum)
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Imaging technologies allow researchers to study from cell and molecular biology to complex biological and pathophysiological systems, contributing significantly to the state of the art in research and to obtaining new insights into scientific and medical problems and challenges not accessible in other ways. In this sense, there is an immense demand for innovation in super-resolution micro…
The proposed application aims to consolidate collaboration between two well-established research groups at the University of São Paulo, Brazil, and the University Medicine of the Johannes-Gutenberg University Mainz, Germany. Here, we propose visits and exchanges of faculty staff, post-docs, and Ph.D. students, which will allow us to develop qualitatively ongoing projects, provide training…
(Only some records are available in English at this moment)
A more recent global health threat or outbreak in the course of the respiratory disease that was named Coronavirus Disease 2019 (COVID-19), is qualified by the virus called SARS-CoV-2. Scientists in basic and clinical areas around the world are having significant effects on the understanding of the pathophysiology and the investigation or effect of drugs with antiviral action and the repo…
(Only some records are available in English at this moment)
Regulatory T (Treg) cells play important role in the maintenance of immunologic tolerance and control of immune responses. The transcription factor Foxp3 is essential for the development, stability and suppressive function of Treg cells. In the last few years, it has been evidenced different metabolic pathways driving the phenotype of Treg cells, which require mitochondrial integrity and …
(Only some records are available in English at this moment)
Extracellular neutrophil traps (NETs) are networks composed of DNA, containing histones and cytotoxic enzymes, which are part of the arsenal to eliminate microorganisms. Initially seen as protective, new evidences demonstrates that NETs can act as a double-edged sword, in addition to microbicidal activity, NETs have deleterious effects in several pathologies. In the tumor microenvironment…
(Only some records are available in English at this moment)
FoxP3+ regulatory T cells (Tregs) play crucial in maintaining immune system homeostasis. However, the molecular signaling mechanisms that drive Treg cell proliferation, differentiation, and function remain not fully understood. The Extracellular Signal-Regulated Kinase 5 (ERK5) is an atypical member of the mitogen-activated protein kinase (MAPK) family protein with canonical kinase functi…
Regulatory T lymphocytes (Tregs) are critical immunosuppressive cells that are crucial in regulating inflammatory responses and maintaining immune homeostasis. Understanding the mechanisms involved in the differentiation, activation, function and stability of Tregs can provide novel therapeutic strategies to halt autoimmune diseases. Immune cells express pattern recognition receptors (PRR…
Th17 cells comprise a subpopulation of CD4 T cells widely described to mediate inflammation in autoimmune diseases. Over the last few years, a range of studies evidenced external and intrinsic factors regulating the transcriptional profile of Th17 cells, thereby affecting their pathogenic potential and revealing their context-dependent plasticity. The adaptor protein STING has been report…
(Only some records are available in English at this moment)
| 5 / 5 | Ongoing research grants |
| 7 / 7 | Completed research grants |
| 9 / 9 | Ongoing scholarships in Brazil |
| 27 / 24 | Completed scholarships in Brazil |
| 8 / 8 | Completed scholarships abroad |
| 56 / 53 | All research grants and scholarships |
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CV Lattes
ORCID