Abstract
Among the major endemical diseases in Latin America, paracoccidioidomycosis (PCM) stands out as a systemic granulomatous disease, caused by Paracoccidioides brasiliensis (P. brasiliensis). Inhalation of fungal conidia may result in asymptomatic infection, acute or chronic disease or sequelae. Murine model studies have established the role of innate and adaptative immunity and factors rela…