CV Lattes
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Universidade de São Paulo (USP). Instituto de Biociências (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Dr. Maria Fernanda Laranjeira da Silva is a Young Researcher in the Department of Physiology at the University of Sao Paulo, Brazil. She received her undergraduate degree in Molecular Sciences (2005) and a Ph.D. (2010) from the University of Sao Paulo, Brazil. Throughout her research career, Dr. Laranjeira da Silva developed a keen focus on host-parasite interactions and the Leishmania´s mechanisms of subverting host defense responses. During her postdoctoral training and a subsequent Research Associate position at the University of Maryland-College Park, U.S.A. with Prof. Norma Andrews and Prof. Iqbal Hamza, she began to investigate iron and heme metabolism pathways in both the parasite and mammalian host. She identified and characterized the first iron exporter (LIR1) in a trypanosomatid parasite answering an important question about how Leishmania prevents accumulation of free iron to avoid cytotoxicity. Moving back to Brazil, Dr. Laranjeira da Silva was given a highly prestigious award from The State of Sao Paulo Research Foundation (FAPESP) and began her independent career as an Early-Career Investigator at the University of Sao Paulo. Her ultimate research goal is to further understand Leishmania pathogenesis to define better therapeutic targets for leishmaniasis treatment. (Source: Lattes Curriculum)
Protozoan parasites of the genus Leishmania are responsible for diseases generally known as leishmaniasis that affect millions of humans around the world. These organisms are digenetic parasites that during the intracellular phase of their life cycle are called amastigotes. The amastigote form inhabits the parasitoforous vacuoles of the mammalian macrophages. The processes leading to the …
Leishmania parasites are the causative agents of a group of diseases collectively known as leishmaniases. These neglected tropical diseases are endemic in Africa, Southeast Asia and South America, where more than 1 billion people live in areas at risk of contracting the disease. There are no available vaccines and the existing treatments are highly toxic and inefficient. It is known that …
Protozoa of the Leishmania genus are responsible for diseases generically known as leishmaniasis that affect humans worldwide. These organisms are parasites that alternate between the invertebrate and vertebrate host where they are able to survive and replicate in macrophages, despite the defense arsenal of these host cells, and from these cells the infection is propagated. One of the cri…
Leishmaniases are a spectrum of diseases caused by protozoan parasites of the genus Leishmania that affect millions of people around the world. Leishmania is transmitted to humans by the bite of infected phlebotomine sandflies. These organisms are digenetic parasites that during the intracellular phase of their life cycle are called amastigotes. The amastigote form inhabits the parasitoph…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 4 / 0 | Completed scholarships in Brazil |
| 10 / 6 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 5 |
| Citations | 18 |
| Cit./Article | 3.6 |
| Data from Web of Science | |
LARANJEIRA-SILVA, MARIA FERNANDA; ZAMPIERI, RICARDO A.; MUXEL, SANDRA M.; FLOETER-WINTER, LUCILE MARIA; MARKUS, REGINA P.. Melatonin attenuates Leishmania (L.) amazonensis infection by modulating arginine metabolism. Journal of Pineal Research, v. 59, n. 4, p. 478-487, NOV 2015. Web of Science Citations: 18. (10/52688-8, 13/13691-1)
AOKI, JULIANA IDE; LARANJEIRA-SILVA, MARIA FERNANDA; MUXEL, SANDRA MARCIA; FLOETER-WINTER, LUCILE MARIA. The impact of arginase activity on virulence factors of Leishmania amazonensis. Current Opinion in Microbiology, v. 52, p. 110-115, DEC 2019. Web of Science Citations: 0. (17/23933-3, 14/50717-1, 16/03273-6, 16/19815-2)
AOKI, JULIANA IDE; HONG, AHYUN; ZAMPIERI, RICARDO ANDRADE; FLOETER-WINTER, LUCILE MARIA; LARANJEIRA-SILVA, MARIA FERNANDA. In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, n. 156, FEB 2020. Web of Science Citations: 0. (17/23933-3)
HONG, AHYUN; ZAMPIERI, RICARDO ANDRADE; SHAW, JEFFREY JON; FLOETER-WINTER, LUCILE MARIA; LARANJEIRA-SILVA, MARIA FERNANDA. One Health Approach to Leishmaniases: Understanding the Disease Dynamics through Diagnostic Tools. PATHOGENS, v. 9, n. 10, OCT 2020. Web of Science Citations: 0. (17/23933-3, 18/23512-0)
LARANJEIRA-SILVA, MARIA FERNANDA; HAMZA, IQBAL; PEREZ-VICTORIA, JOSE M.. Iron and Heme Metabolism at the Leishmania-Host Interface. Trends in Parasitology, v. 36, n. 3, p. 279-289, MAR 2020. Web of Science Citations: 0. (17/23933-3)
(References retrieved automatically from State of São Paulo Research Institutions)
SILVA, Maria Fernanda Laranjeira da. Relação entre a localização celular da enzima arginase de Leishmania (Leishmania) amazonensis e seu papel na infecção de macrófagos murinos. Tese (Doutorado) - Instituto de Biociências. Universidade de São Paulo (USP). São Paulo. (06/50482-8)