CV Lattes
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Universidade de São Paulo (USP). Faculdade de Odontologia (FO) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduate at Faculdade de Odontologia from Universidade de Mogi das Cruzes (1980), especialized in Oral Pathology, master in Dental Clinics from Universidade de São Paulo (1988) and Ph.D. in Dentistry (Oral Pathology) from Universidade de São Paulo (1991). Research Fellow at the Cell Biology Laboratory, NIH-NIDCD (1995), and Research Fellow at the Laboratory of Molecular Biology on Cell Regeneration and Development, NIH-NIDCD (1997). Currently is Full Professor at University of São Paulo, Chief of the Laboratory of Molecular Pathology, Associate Editor of the journal Clinical and Laboratorial Research in Dentistry. Has experience in Odontology, acting on the following subjects: patologia bucal, biologia molecular, carcinoma epidermóide, câncer de boca and odontologia. (Source: Lattes Curriculum)
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In the present study, we evaluated and described the sensitivity of the stem cell marker B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) in identifying early lesions of carcinoma ex pleomorphic adenoma. While invasive carcinomas ex pleomorphic adenomas are tumors with a prominent and easily recognizable malignant component, the identification of early carcinomatou…
Oral squamous cell carcinoma is the most prevalent neoplasia of oral cavity. The comprehension of this neoplasia is limited regarding its origin and which cells are involved in tumor development and progression, becoming a challenge to the establishment of effective treatment and preventive strategies. In view of this, the identification of neoplastic cells subpopulations on oral squamou…
The oral squamous cell carcinoma is a common cancer disease with tobacco and alcohol consumption as main risk factors. Nowadays, patient's survival in five years after the disease diagnosis is low, although the efforts in cancer research and the progress in diagnosis and therapy strategies. The presence of lymph node metastasis is one of most important prognosis indicator of oral squamous…
(Only some records are available in English at this moment)
Among the malignant tumors of the salivary gland, mucoepidermoid carcinoma (MUC) is the most prevalent. With a high resistance to conventional antitumor treatment, radiotherapy-associated surgery is the current elective treatment for MUC, leaving severe sequelae and compromising the quality of life of the affected individuals. In general, salivary gland tumors respond poorly to chemothera…
Oral squamous cell carcinoma (OSCC) is the most prevalent neoplasia of oral cavity both in the world and in Brazil and its prognosis has not changed despite advances in knowledge of this neoplasm. We know that is a genetic disease that develops through multiple mutations which cause deregulation of the basic functions of the cell. Recently, was reported that head and neck squamous cell ca…
Oral squamous cell carcinoma (OSCC) is the most prevalent neoplasia of oral cavity. The comprehension of this neoplasia is limited regarding its origin and which cells are involved in tumor development and progression, difficulting to establish an effective treatment and preventive strategies. The identification of neoplastic cells subpopulations on oral squamous cell carcinoma fundament…
(Only some records are available in English at this moment)
The initiation, growth, recurrence and metastasis of solid tumours, including oral squamous cell carcinoma (OSCC), have been related to the behaviour of a small subpopulation of 'tumour-initiating' cells. These cells, also called as cancer stem cells, drive tumour growth and are responsible for tumour aggressiveness and therapeutic resistance. One such targeted therapy of importance for t…
| 17 / 11 | Completed research grants |
| 18 / 11 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 36 / 23 | All research grants and scholarships |
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