CV Lattes
Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biociências (IBB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Mariana Fernandes Machado in research grants and scholarships supported by FAPESP.
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
The inefficiency of in vitro maturation (IVM) compared to in vivo maturation is due to spontaneous resumption of meiosis I in the oocyte when removed from the ovarian follicle. The cAMP is a key molecule that regulates oocyte maturation. A decrease in the oocyte cAMP leads to premature resumption of meiosis I and asynchrony between the nuclear and cytoplasmic maturation. Several substance…
The SPOM system (simulated physiological oocyte maturation) consists of a prolonged period of maturation while the delayed nuclear maturation by addition of agents which maintains cAMP at high concentrations in the oocyte. The success of SPOM in mouse embryos and cattle in vitro production led to more detailed research on the cellular and molecular mechanisms of this system which constitu…
| 3 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 4 / 2 | All Scholarships |
| Associated processes | |