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Ivone Carvalho

CV Lattes GoogleMyCitations ResearcherID ORCID


Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

She completed a PhD in Organic Chemistry in the Chemistry Institute at University of Sao Paulo (1991), and Post-doctorate studies in the laboratory of Prof. Alan A. Haines at the University of East Anglia (UEA), England, in Carbohydrate Chemistry (1995-1997, two years) and Post-doctorate in the laboratory of Prof. Robert A. Field at the University of St Andrews, Scotland, in Glycopeptide Chemistry (2000, 6 months). She started her independent career at the School of Pharmaceutical Sciences f Ribeirao Preto, University of Sao Paulo, where she became a lecturer in Medicinal Chemistry in 1987. In 2003, she was appointed as Associate Professor and in 2009 was promoted to Full Professor. Currently, IC is a member of the Carbohydrate Research Editorial Board. Her research focuses on the design, synthesis and evaluation of compounds with potential biological activities, mainly related to carbohydrate, such as mono-, di-, and oligosaccharides and iminosugar and carbasugar, and glycopeptide, as well as heterocycles having quinazoline, quinoline, 3,5-diketopiperazine nucleus and 1,2,3-triazole scaffolds, using ?Click Chemistry?. Chemical approaches are used to develop agents to specifically target a known physiological/pathological pathway of T. cruzi in the course of Chagas and Alzheimer diseases, tumour and diabetes. She has CNPq scholarship Research Productivity 1C. In the period from 2005 to 2008 she was President of the FCFRP-USP Undergraduate Commission and from 2009 to 2010 was deputy of the Head of the Department of Pharmaceutical Sciences. Currently, she is a member of the Congregation and Sector Assessment Commission for progression in the teaching career, Pharmacy Area University of São Paulo. She published 82 articles in International and National Journals, being 34 articles related to carbohydrate synthesis and biological evaluation with co-authors from International Community, 15 book chapters, 03 patents and 164 abstracts presented in Congress and participated in 125 events. She received the award of Tetrahedron as the Most Cited Paper 2006-2009, Elsevier and between 2010 and 2011; IC was the Top 25 cited author of Bioorganic Medicinal Chemistry and Tetrahedron (Elsevier). She supervised 07 Post-doc, 11 PhD theses, 17 Master and, currently, the research group is formed by 02 PhD students and 012Master and 05 co-workers. Research ID: C-5806-2012 and Orcid code: 0000-0002-2028-777X; Her work in the Carbohydrate area was recognized by Elsevier Editors, who invited her to become a member of the Editorial board of the Carbohydrate Research since 2015. Currentely, she is the Brazilian representative at ICO (International Carbohydrate Organization). (Source: Lattes Curriculum)

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FAPESP support in numbers * Updated January 18, 2020
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (15)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications15
Citations69
Cit./Article4.6
Data from Web of Science

CHIERRITO, TALITA P. C.; PEDERSOLI-MANTOANI, SUSIMAIRE; ROCA, CARLOS; SEBASTIAN-PEREZ, VICTOR; MARTINEZ-GONZALEZ, LORETO; PEREZ, DANIEL I.; PEREZ, CONCEPCION; CANALES, ANGELES; JAVIER CANADA, F.; CAMPILLO, NURIA E.; et al. Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 145, p. 431-444, . Web of Science Citations: 7. (13/50788-3, 12/04054-5, 12/14114-5, 14/10414-0)

CAMPO, VANESSA LEIRIA; MARCHIORI, MARCELO FIORI; CARVALHO, IVONE. Insights into Anti-Trypanasornal Agents Based on Synthetic Glycoconjugates. CURRENT TOPICS IN MEDICINAL CHEMISTRY, v. 18, n. 5, p. 382-396, . Web of Science Citations: 3. (12/19390-0)

ZAMONER, LUIS O. B.; ARAGAO-LEONETI, VALQUIRIA; CARVALHO, IVONE. Iminosugars: Effects of Stereochemistry, Ring Size, and N-Substituents on Glucosidase Activities. PHARMACEUTICALS, v. 12, n. 3, . Web of Science Citations: 0. (07/00910-6)

MANTOANI, SUSIMAIRE PEDERSOLI; DE ANDRADE, PETERSON; CANTUARIA CHIERRITO, TALITA PEREZ; FIGUEREDO, ANDREZA SILVA; CARVALHO, IVONE. Potential Triazole-based Molecules for the Treatment of Neglected Diseases. Current Medicinal Chemistry, v. 26, n. 23, p. 4403-4434, . Web of Science Citations: 2. (08/00373-3)

IGUAL, MICHELLE O.; NUNES, PAULO S. G.; DA COSTA, RAFAEL M.; MANTOANI, SUSIMAIRE P.; TOSTES, RITA C.; CARVALHO, IVONE. Novel glucopyranoside C2-derived 1,2,3-triazoles displaying selective inhibition of O-GlcNAcase (OGA). Carbohydrate Research, v. 471, p. 43-55, . Web of Science Citations: 2. (16/04003-2)

CAMPO, VANESSA LEIRIA; RIUL, THALITA B.; BORTOT, LEANDRO OLIVEIRA; MARTINS-TEIXEIRA, MARISTELA B.; MARCHIORI, MARCELO FIORI; IACCARINO, EMANUELA; RUVO, MENOTTI; DIAS-BARUFFI, MARCELO; CARVALHO, IVONE. A Synthetic MUC1 Glycopeptide Bearing GalNAc-Thr as a Tn Antigen Isomer Induces the Production of Antibodies against Tumor Cells. CHEMBIOCHEM, v. 18, n. 6, p. 527-538, . Web of Science Citations: 3. (12/19390-0)

MANTOANI, SUSIMAIRE P.; CHIERRITO, TALITA P. C.; VILELA, ADRIANA F. L.; CARDOSO, CARMEN L.; MARTINEZ, ANA; CARVALHO, IVONE. Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors. Molecules, v. 21, n. 2, . Web of Science Citations: 19. (13/50788-3, 13/01710-1, 12/04054-5, 12/14114-5)

GONCALVES NUNES, PAULO SERGIO; ZHANG, ZHENGXING; KUO, HSIOU-TING; ZHANG, CHENGCHENG; ROUSSEAU, JULIE; ROUSSEAU, ETIENNE; LAU, JOSEPH; KWON, DANIEL; CARVALHO, IVONE; BENARD, FRANCOIS; et al. Synthesis and evaluation of an F-18-labeled trifluoroborate derivative of 2-nitroimidazole for imaging tumor hypoxia with positron emission tomography. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, v. 61, n. 4, p. 370-379, . Web of Science Citations: 0. (17/04599-5)

CHIERRITO, TALITA P. C.; PEDERSOLI-MANTOANI, SUSIMAIRE; ROCA, CARLOS; REQUENA, CARLOS; SEBASTIAN-PEREZ, VICTOR; CASTILLO, WILLIAN O.; MOREIRA, NATALIA C. S.; PEREZ, CONCEPCION; SAKAMOTO-HOJO, ELZA T.; TAKAHASHI, CATARINA S.; et al. From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 139, p. 773-791, . Web of Science Citations: 13. (13/50788-3, 12/04054-5, 12/14114-5)

MARCHIORI, MARCELO FIORI; RIUL, THALITA B.; BORTOT, LEANDRO OLIVEIRA; ANDRADE, PETERSON; JUNQUEIRA, GETULIO G.; FOCA, GIUSEPPINA; DOTI, NUNZIANNA; RUVO, MENOTTI; DIAS-BARUFFI, MARCELO; CARVALHO, IVONE; et al. Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion. Bioorganic & Medicinal Chemistry, v. 25, n. 21, p. 6049-6059, . Web of Science Citations: 2. (12/19390-0)

FIGUEREDO, ANDREZA S.; ZAMONER, LUIS O. B.; REJZEK, MARTIN; FIELD, ROBERT A.; CARVALHO, IVONE. Cluster glycosides and heteroglycoclusters presented in alternative arrangements. Tetrahedron Letters, v. 59, n. 50, p. 4405-4409, . Web of Science Citations: 1. (13/27038-8)

CAMPO, VANESSA L.; IVANOVA, IRINA M.; CARVALHO, IVONE; LOPES, CARLA D.; CARNEIRO, ZUMIRA A.; SAALBACH, GERHARD; SCHENKMAN, SERGIO; DA SILVA, JOAO SANTANA; NEPOGODIEV, SERGEY A.; FIELD, ROBERT A.. Click chemistry oligomerisation of azido-alkyne-functionalised galactose accesses triazole-linked linear oligomers and macrocycles that inhibit Trypanosoma cruzi macrophage invasion. Tetrahedron, v. 71, n. 39, SI, p. 7344-7353, . Web of Science Citations: 14. (12/19390-0)

CHIERRITO, TALITA P. C.; PEDERSOLI-MANTOANI, SUSIMAIRE; ROCA, CARLOS; REQUENA, CARLOS; SEBASTIAN-PEREZ, VICTOR; CASTILLO, WILLIAN O.; MOREIRA, NATALIA C. S.; PEREZ, CONCEPCION; SAKAMOTO-HOJO, ELZA T.; TAKAHASHI, CATARINA S.; et al. From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 139, p. 773-791, . Web of Science Citations: 13. (13/50788-3, 12/04054-5, 12/14114-5)

MARCHIORI, MARCELO FIORI; RIUL, THALITA B.; BORTOT, LEANDRO OLIVEIRA; ANDRADE, PETERSON; JUNQUEIRA, GETULIO G.; FOCA, GIUSEPPINA; DOTI, NUNZIANNA; RUVO, MENOTTI; DIAS-BARUFFI, MARCELO; CARVALHO, IVONE; et al. Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion. Bioorganic & Medicinal Chemistry, v. 25, n. 21, p. 6049-6059, . Web of Science Citations: 2. (12/19390-0)

FIGUEREDO, ANDREZA S.; DE ANDRADE, PETERSON; RIUL, THALITA B.; MARCHIORI, MARCELO F.; DE LEO, THAIS CANASSA; FLEURI, ANNA KAROLINE A.; SCHENKMAN, SERGIO; BARUFFI, MARCELO D.; CARVALHO, IVONE. Galactosyl and sialyl clusters: synthesis and evaluation against T. cruzi parasite. Pure and Applied Chemistry, v. 91, n. 7, p. 1191-1207, . Web of Science Citations: 0. (13/27038-8)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

FIGUEREDO, Andreza da Silva. Síntese e avaliação biológica de glycoclusters com potencial aplicação para o tratamento de diabetes e doença de Chagas. 2018. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

MOROTTI, Ana Luísa Malaco. Síntese de análogos de âncora de GPI: uma contribuição para a descoberta de novos alvos moleculares de Trypanosoma cruzi. 2018. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

GOMES, Adriane da Silveira. Síntese e modelagem molecular de carboidratos com potencial atividade anti-glucosidase. 2008. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

KAWANO, Daniel Fábio. Síntese de derivados do fator de agregação plaquetária imobilizados em resina e identificação do correspondente receptor em Trypanosoma Cruzi. 2010. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

ANDRADE, Peterson de. Planejamento, síntese e avaliação da atividade biológica de potenciais inibidores da enzima trans-sialidase de Trypanosoma cruzi. 2012. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

GALO, Oswaldo Aparecido. Síntese de análogos de benznidazol por \"click chemistry\" e avaliação de atividade antiparasitária. 2012. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

VOLPINI, Josiana Garcia de Araujo. Planejamento e relação estrutura-atividade de inibidores da MARK3 em câncer de cabeça e pescoço. 2010. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

IGUAL, Michelle Ogava. Planejamento, síntese e avaliação biológica de novos inibidores seletivos da hidrolase O-GlcNAcase (OGA). 2018. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

CHIERRITO, Talita Perez Cantuaria. Síntese de potencial inibidor de acetilcolinesterase para tratamento da Doença de Alzheimer. 2016. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

CAMPO, Vanessa Leiria. Síntese e atividade de glicopeptídeos de interesse no planejamento de fármacos inibidores de \'trans-sialidade de Trypanosoma cruzi\'. 2007. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

PINSETTA, Flávio Roberto. Síntese e relação estrutura-toxicidade de derivados aminoglicosídeos como potenciais protótipos na busca de um fármaco seguro para o tratamento da Doença de Ménière. 2010. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

Patent applications

ANÁLOGOS DE BENZNIDAZOL E PROCESSOS DE SÍNTESE DE ANÁLOGOS DE BENZNIDAZOL BR1020130277428 - Universidade de São Paulo (USP). Ivone Carvalho; João Santana Da Silva; Oswaldo Aparecido Galo; Renata Sesti Costa; Peterson De Andrade - October 2013, 29

Solicitação em análise e dentro do prazo legal de sigilo previsto na legislação BR1020180045997 - Universidade de São Paulo (USP). Solicitação em análise e dentro do prazo legal de sigilo previsto na legislação - March 2018, 08

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