Professor at the Department of Animal Morphology and Physiology at the Faculty of Agricultural and Veterinary Sciences (Campus Jaboticabal) at the São Paulo State University "Júlio de Mesquita Filho" (DMFA/FCAV/UNESP). Collaborating researcher and advisor at the Graduate Program in Anatomy of Domestic and Wild Animals at the Faculty of Veterinary Medicine and Animal Sciences - University of São Paulo (FMVZ-USP). Its line of research is the development of biomaterials derived from decellularized organs, aiming the production of functionalized biomaterials to be applied in Regenerative Veterinary Medicine.Graduated in Animal Science (2008) at the Faculty of Agricultural and Technological Sciences (FCAT-UNESP). Master (2011) and Doctor (2015) at FMVZ-USP, with a sandwich doctorate period at Universitè Laval (Quebec, CAN). During her graduate studies, the main research topic was placentation in various animal models, within the areas of morphology, reproductive immunology, cellular and molecular biology and epigenetics. (Source: Lattes Curriculum)
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The aim of this project is to develop a biomaterial produced by decellularization of bovine placentas that can be used as a bone graft after osteogenic differentiation of cultured canine mesenchymal stem cells. For this, canine mesenchymal cells will be enzymatically isolated from adipose tissue and in parallel the bovine placenta will be decellularized. After the placenta decellularizati…
In placentas from bovine pregnancies produced by nuclear transfer of somatic cell (NTSC) extracellular matrix (ECM) is hyperplasic in maternal side of placentome, and trophoblastic giant cells increase their population and invasiveness. Those two mechanisms, hyperplasia and invasiveness, are similar to those that occur in tumorigenesis, suggesting that placenta is a good model for tumorig…
During bovine placentation a strict trophoblastic invasion occurs trigged by trophoblastic giant cells (TGC) which fusion with uterine epithelial cells, ending in hybrids cells. This cells are them degradated or absorbed by the trophoblast or delivery substances and free-fetal DNA (fDNA) in maternal blood flow, likewise in human cytotophoblast. fDNA identification in maternal serum effect…
Actually the nuclear transfer is the most utilized technique in cloning of young and adult individual, however the success rate still low and associated with placental alterations caused by epigenetic deregulation of imprinted genes in embryogenesis, due to incomplete nuclear reprogramming. For better efficiency of nuclear transfer, should be required more accurate methods for selection o…
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| 1 / 1 | Completed research grants |
| 4 / 4 | Completed scholarships in Brazil |
| 5 / 5 | All research grants and scholarships |
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CV Lattes
ORCID