Abstract
The increase in life expectancy of the populations has fostered the interest in the understanding of the ageing process. This process, called immunosenescence, is associated with an immunedysregulation, notably of the Th-1/Th-2 balance, with progressive predominance of Th-2 responses. Decreased IFN-g secretion and increased IL-4 and IL-10 secretion are seen in lymphocytes from aged as com…