CV Lattes
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduated in Pharmacy-Biochemistry, Drugs and Medicines module, from the School of Pharmaceutical Sciences of Ribeirão Preto FCFRP-USP (2007), where she got the Master of Science degree concentration area Natural and Synthetic Products (2008-2010), on the synthesis of cyclic dipeptides and glycoconjugate chemistry applied to the study of mucins of tumour and parasitic cells. From the same Graduate Programme of this institution, she got the Doctor of Philosophy degree (2014-2018), synthesising new glycosidic derivatives of daunorubicin and doxorubicin, aiming to obtain antitumour anthracyclines with lower toxicity and susceptibility to multidrug resistance. In the Ministry of Agriculture, Livestock and Food Supply, she worked in the National Agricultural Laboratory in Campinas Lanagro-SP (2008-2011), developing and validating analytical methods and performing official control analyses of residues and contaminants in foods of animal and plant origin, and of physicochemical quality in veterinary medicines; and in the Regional Technical Unit of Agriculture, Livestock and Food Supply in Ribeirão Preto UTRA-RAO (2011-2015, 2018-present), in the regulation and inspection of manufacturing industries and veterinary products of pharmaceutical and biological nature. (Source: Lattes Curriculum)
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Doxorubicin is an antineoplastic drug belonging to the anthracyclines class, which lies amongst the most effective chemotherapeutics in clinical use for cancer treatment. They are constituted by a quinone/hydroquinone-type ring system and a glycosidic unit called daunosamine, and act as DNA-intercalating agents, oxidative stress inductors and topoisomerase II poisons, the main mechanisms …
2,5-diketopiperazines are cyclic dipeptides, found in various natural products. Diverse biological activities of these compounds have been described, amongst which there are: inhibition of PAI-1 (plasminogen activator inhibitor-1); antitumor and antimicrobial activity; inhibition of alpha-glucosidase and glycogen phosphorylase enzymes; action on GABA and 5HT receptors. Although the majori…
Doxorubicin is an anthracycline classified among the most effective chemotherapeutics against cancer. It is comprised by 3-amino-2,3,6-deoxy-L-fucose (daunosamine) linked to a quinone-hydroquinone system, and acts by DNA-intercalation, oxidative stress generation and topoisomerase II poisoning. Regardless of its therapeutic value, multidrug resistance and severe cardiotoxicity are importa…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
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