- Research Grants
bachelor's at Ciências Biológicas from Universidade de São Paulo (2007) and master's at Genetics from Universidade de São Paulo (2010). Has experience in Morphology, focusing on Cytology and Celular Biology, acting on the following subjects: aneuploidy, mitosis and confocal microscopy. (Source: Lattes Curriculum)
Asymmetric cell division is a striking feature of stem cells. It generates two daughter cells with defined distinct fates, ensuring both stem cell self renewal and differentiation. Abnormalities in this process may affect tissue homeostasis leading to tumor formation, as first observed in Drosophila mutants for genes involved in asymmetric cell division. Failures in asymmetric cell divi...
Hippo pathway is a phosphorylation cascade that culminates in YAP inactivation, inhibiting its activity as a transcription factor. Initially, Hippo pathway was related to the control of cell proliferation, tissue growth and stem cells phenotype. In addition, the inhibition of this pathway and hyperactivation of YAP have been related to several types of cancer. Efforts have been done to ...
Aneuploidy is a characteristic associated with aggressiveness of solid tumors. Aneuploid cells can result from many errors during mitosis, including defects in chromatid cohesion, abnormalities in the mitotic checkpoint, errors or hyperstabilized interactions between microtubules and kinetochores connection, centrossome amplification, multipolar mitosis and cytokinesis failure. As many ...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|