graduate at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1990), master's at Anatomy from Universidade Estadual Paulista Júlio de Mesquita Filho (1993) and ph.d. at Anatomy from Universidade Estadual Paulista Júlio de Mesquita Filho (1996). Has experience in Morphology, focusing on Human Anatomy, acting on the following subjects: biologia celular e estrutural, prostate, morfologia, ultra-estrutura and próstata. (Source: Lattes Curriculum)
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Prostatic cancer is the second-highest type of cancer around of the world. Processes related to pathogenesis and progression of prostatic cancer such as inflammation and angiogenesis are pointed out as being fundamental factors for lesion development, leading to the repetition of tissue damage and regeneration and to glandular microenvironment imbalance. Thus, these processes are importan…
Prostate cancer (CaP) is the most diagnosed type of cancer in human beings. Literature has correlated hypelipic diet intake with prostate cancer progression. In addition to this, it is known that antioxidants, such as polyphenols, have been evaluated in cancer therapies. The Jaboticaba, a natural antioxidant, is being studied and shows the antiproliferative and antioxidant effects on the…
Aging and obesity are factors which are deeply related to prostate alterations, involving the epithelium and the stroma, leading to oxidative stress, cellular proliferation and inflammatory process. The Jaboticaba (Type of black berry) shows a large variety of phenolics and anthocyanins, known to have effects in anti-inflammatory activity, hormone regulation and weight gain reduction. Thu…
Senescence is related to changes in the hormonal environment causing to morphological and functional prostatic disturbance. The aim of this work was to evaluate and compare the effects of anti-inflammatory treatments, administering celocoxib and goniothalamin on the structural and molecular biology of the ventral prostate of senile mice (FVB) and TRAMP. The IL-6, IL1²- e IL-17, TNF-2, …
(Only some records are available in English at this moment)
Prostate cancer (PCa) is the second leading cause of cancer death among men. Approximately patients 30% show recurrence of the disease after treatment, who initially responds to androgen deprivation therapy (ADT), and may progress to a therapy resistance PCa, turning into castration-resistance prostate cancer (CRPC). Several therapies are being developed in order to delay or prevent the d…
Prostate Cancer is the second leading cause of Cancer deaths worldwide. In Brazil it's the second most common Cancer, behind only Non-Melanoma Skin Cancer. Of the Prostate Cancer pathogenesis aspects, inflammation is an important axis for its development and progression, leading to the repeated process of tissue damage and regeneration that creates an unbalanced microenvironment of inflam…
Prostate cancer (PCa) is the second cause of death among men. During PCa development and progression several processes are involved, highlighting the inflammation. Molecules that participate in the inflammatory process lead to the glandular microenvironment changes, favoring the PCa development and progression. Among these molecules, cyclooxygenase-2 (COX-2) and inducible nitric oxide syn…
Aging is a very important factor on prostate morphological and functional alterations. And also, obesity and/or overweight, are factors involved in promoting metabolic changes, contributing to occurrence of prostate damages. Currently altenative methods, using natural products, have been evaluated as prostate injury treatment. The Jaboticaba has been studied due to possible antioxidant an…
Prostate cancer is the sixth most common type of cancer in the world and the most prevalent in men, considering the aging process. Different studies of prostate lesions, including its prevention and treatment, have been evaluated. The antiangiogenic drugs with antiproliferative properties such as Nintedanib (BIBF-1120) have received special attention due to positive results in the prostat…
(Only some records are available in English at this moment)
Prostate cancer is the most common type of cancer in men and the second leading cause of death, particularly in men over 50 years old. This disease has been widely studied due to the large number of individuals affected by this type of injury, in addition to the cancer development complexity, considering the important epithelial-stromal interaction as a primary factor for alterations. Pro…
| 1 / 1 | Ongoing research grants |
| 12 / 5 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 20 / 13 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 36 / 22 | All research grants and scholarships |
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CV Lattes
ORCID