CV Lattes
ResearcherID
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Holds a bachelor's degree in Biological Sciences from the Institute of Biosciences of the University of São Paulo (2007) and a PhD in Sciences from the Institute of Biomedical Sciences of the University of São Paulo (2012). Postdoctoral research fellow from the Department of Anatomy ICB / USP (2013-2016) and IIEP / Israelita Albert Einstein Hospital (2017). Worked as a Visiting Associate Researcher at the University of Reading (2014-2015). Since 2017, appointed as a Lecturer at Medical Course from Universidade Nove de Julho, working mainly on the following topics: oncology and endocrinology of adrenal cortex, and endocrine neurophysiology of HPA axis. (Source: Lattes Curriculum)
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Studies using knock-out mice models for the gene pro-opiomelanocortin (Pomc-/-) have demonstrated that animals which survive to adult were obese, with defects in pigmentation and had severe adrenal insufficiency. When newborns, adrenal gland was present macroscopically, however, five weeks after the birth, there is a severe atrophy of the entire organ, reflecting the dependency of POMC de…
The adrenocorticotropic hormone (ACTH) is considered the main peptide derived from POMC acting on the adrenal gland promoting development, maintenance and corticosteroidogenesis. However, there is considerable evidence that other peptides derived from POMC, such as those from the N-terminal (N-POMC), might act to maintain the adrenal gland. However, it remains unknown the receptor for the…
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