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Chung Man Chin

CV Lattes GoogleMyCitations


Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR)  (Institutional affiliation for the last research proposal)
Birthplace: China

Graduated in Pharmacy UNESP ( University of Sao Paulo State), Masters in Pharmacology, Faculty of Medicine of Ribeirão Preto-USP University of Sao Paulo and a PhD (Faculty of Pharmaceutical Sciences at USP ?SP). She is currently Associate Professor, Medicinal Chemistry in the School of Pharmaceutical Sciences, UNESP, Araraquara. She has experience in design and synthesis of drugs and prodrugs (antimicrobial anti-inflammatory , neglected diseases, especially Chagas Disease , leprosy, schistosomiasis, malaria, tuberculosis and sickle cell anemia). She is coordinator of Lapdesf - Laboratory of Drug Design FCF / UNESP. Participates in Project Network Nanobiotec 2008 and she has research projects in cooperation Pharmaceutical Industry / University since 2003, designing new drugs with patent award in U.S. A ,EC and China. She has participate as invited speaker in several internacional and national conferences (India, Greece, Russia, Egypt), whose contacts generated partnership in research and exchange graduate students with the University of Freiburg (Germany), Vrijet Universitet - Brussels (Belgium ), Universidad de la República - Montevideo (Uruguay) and Universidad Nacional de Salta (Argentina). She is adviser (masters and doctorate) in the Graduate Program in Pharmaceutical Sciences FCF-UNESP. She is president of the Pharmaceutical Association of Araraquara (AFAR) and coordinator and lecturer of the course "Pharmacotherapy and Drug Interactions" for professional updating by AFAR since 1999 is invited professor of the specialization course in ?Pharmaceutical Care? at the Federal University of Alfenas since 2005. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher
Brazilian drug shows good results against sickle cell anemia 
Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated October 24, 2020
Total / Available in English
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (20)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications17
Citations226
Cit./Article13.3
Data from Web of Science

CHUNG, MAN-CHIN; GUIDO, RAFAEL VICTÓRIO CARVALHO; MARTINELLI, TATIANE FAVARATO; GONÇALVES, MARINEI FERREIRA; POLLI, MICHELLE CARNEIRO; BOTELHO, KATIA CIRLENE ALVES; VARANDA, ELIANA APARECIDA; COLLI, WALTER; MIRANDA, M. TERÊSA M.; FERREIRA, ELIZABETH IGNE. Synthesis and in vitro evaluation of potential antichagasic hydroxymethyinitrofurazone (NFOH-121): A new nitrofurazone prodrug. Bioorganic & Medicinal Chemistry, v. 11, n. 22, p. 4779-4783, . (95/04562-3, 01/01192-3)

CHELUCCI, RAFAEL C.; DE OLIVEIRA, ISABELA J.; BARBIERI, KARINA P.; LOPES-PIRES, MARIA E.; POLESI, MARISA C.; CHIBA, DIEGO E.; CARLOS, IRACILDA Z.; MARCONDES, SISI; DOS SANTOS, JEAN L.; CHUNG, MANCHIN. Antiplatelet activity and TNF- release inhibition of phthalimide derivatives useful to treat sickle cell anemia. MEDICINAL CHEMISTRY RESEARCH, v. 28, n. 8, p. 1264-1271, . Web of Science Citations: 0. (15/19531-1, 13/23461-3)

SANTOS FERNANDES, GUILHERME FELIPE; BERNARDES SILVA, GABRIEL DALIO; PAVAN, ALINE RENATA; CHIBA, DIEGO EIDY; CHIN, CHUNG MAN; DOS SANTOS, JEAN LEANDRO. Epigenetic Regulatory Mechanisms Induced by Resveratrol. NUTRIENTS, v. 9, n. 11, . Web of Science Citations: 19. (15/19531-1, 16/08470-4, 16/08880-8, 16/09502-7)

LORENA BLAU; RENATO FARINA MENEGON; MAN CHIN CHUNG. Pró-fármaco ativado por enzima, uma estratégia promissora na quimioterapia. Química Nova, v. 29, n. 6, p. 1307-1317, . (01/01192-3)

YAMASAKI, PAULO RENATO; DO NASCIMENTO, DEJAIR CAETANO; CHELUCCI, RAFAEL CONSOLIN; FERNANDES BELONE, ANDREA DE FARIA; ROSA, PATRICIA SAMMARCO; DIORIO, SUZANA MADEIRA; FERREIRA DE MELO, THAIS REGINA; BARBIERI, KARINA PEREIRA; POLESI PLACERES, MARISA CAMPOS; CARLOS, IRACILDA ZEPONE; et al. Synthesis and evaluation of novel dapsone-thalidomide hybrids for the treatment of type 2 leprosy reactions. Bioorganic & Medicinal Chemistry Letters, v. 24, n. 14, p. 3084-3087, . Web of Science Citations: 6. (12/50359-2)

DOS SANTOS, JEAN LEANDRO; VARANDA, ELIANA A.; LIMA, LIDIA MOREIRA; CHIN, CHUNG MAN. Mutagenicity of New Lead Compounds to Treat Sickle Cell Disease Symptoms in a Salmonella/Microsome Assay. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 11, n. 2, p. 779-788, . Web of Science Citations: 8. (07/56115-0)

SCARIM, CAUE B.; CHELUCCI, RAFAEL C.; DOS SANTOS, JEAN L.; CHIN, CHUNG M.. The Use of Sulfonamide Derivatives in the Treatment of Trypanosomatid Parasites including Trypanosoma cruzi, Trypanosoma brucei, and Leishmania ssp. Medicinal Chemistry, v. 16, n. 1, p. 24-38, . Web of Science Citations: 0. (16/10847-9)

SCARIM, CAUE B.; CHIN, CHUNG M.. Current Approaches to Drug Discovery for Chagas Disease: Methodological Advances. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, v. 22, n. 8, p. 509-520, . Web of Science Citations: 0. (16/10847-9)

MENDES MACHADO, MARCELLA GABRIELLE; SCARIM, CAUE BENITO; DE ANDRADE, CLEVERTON ROBERTO; DOS SANTOS, JEAN LEANDRO; CHIN, CHUNG MAN. Synthesis and anti-inflammatory intestinal activity of new glucocorticoid derivatives. MEDICINAL CHEMISTRY RESEARCH, v. 29, n. 2, . Web of Science Citations: 0. (14/08728-6)

SCARIM, CAUE BENITO; CHIN, CHUNG MAN. Nitroheterocyclic derivatives: privileged scaffold for drug development against Chagas disease. MEDICINAL CHEMISTRY RESEARCH, v. 28, n. 12, p. 2099-2108, . Web of Science Citations: 0. (16/10847-9)

BARBOSA, C. F.; OKUDA, E. S.; CHUNG, M. C.; FERREIRA, E. I.; CICARELLI, R. M. B.. Rapid test for the evaluation of the activity of the prodrug hydroxymethylnitrofurazone in the processing of Trypanosoma cruzi messenger RNAs. Brazilian Journal of Medical and Biological Research, v. 40, n. 1, p. 33-39, . (01/01192-3)

DOS SANTOS, JEAN LEANDRO; LANARO, CAROLINA; LIMA, LIDIA MOREIRA; GAMBERO, SHELEY; FRANCO-PENTEADO, CARLA FERNANDA; AEXANDRE-MOREIRA, MAGNA SUZANA; WADE, MARLENE; YERIGENAHALLY, SHOBHA; KUTLAR, ABDULLAH; MEILER, STEFFEN E.; et al. Design, Synthesis, and Pharmacological Evaluation of Novel Hybrid Compounds To Treat Sickle Cell Disease Symptoms. Journal of Medicinal Chemistry, v. 54, n. 16, p. 5811-5819, . Web of Science Citations: 27. (07/56115-0, 10/12495-6)

SCARIM, CAUE B.; CHELUCCI, RAFAEL C.; DOS SANTOS, JEAN L.; CHIN, CHUNG M.. The Use of Sulfonamide Derivatives in the Treatment of Trypanosomatid Parasites including Trypanosoma cruzi, Trypanosoma brucei, and Leishmania ssp. Medicinal Chemistry, v. 16, n. 1, p. 24-38, . Web of Science Citations: 0. (16/10847-9)

MENDES MACHADO, MARCELLA GABRIELLE; SCARIM, CAUE BENITO; DE ANDRADE, CLEVERTON ROBERTO; DOS SANTOS, JEAN LEANDRO; CHIN, CHUNG MAN. Synthesis and anti-inflammatory intestinal activity of new glucocorticoid derivatives. MEDICINAL CHEMISTRY RESEARCH, v. 29, n. 2, . Web of Science Citations: 0. (14/08728-6)

CHUNG, MAN-CHIN; GUIDO, RAFAEL VICTÓRIO CARVALHO; MARTINELLI, TATIANE FAVARATO; GONÇALVES, MARINEI FERREIRA; POLLI, MICHELLE CARNEIRO; BOTELHO, KATIA CIRLENE ALVES; VARANDA, ELIANA APARECIDA; COLLI, WALTER; MIRANDA, M. TERÊSA M.; FERREIRA, ELIZABETH IGNE. Synthesis and in vitro evaluation of potential antichagasic hydroxymethyinitrofurazone (NFOH-121): A new nitrofurazone prodrug. Bioorganic & Medicinal Chemistry, v. 11, n. 22, p. 4779-4783, . (95/04562-3, 01/01192-3)

CHELUCCI, RAFAEL C.; DE OLIVEIRA, ISABELA J.; BARBIERI, KARINA P.; LOPES-PIRES, MARIA E.; POLESI, MARISA C.; CHIBA, DIEGO E.; CARLOS, IRACILDA Z.; MARCONDES, SISI; DOS SANTOS, JEAN L.; CHUNG, MANCHIN. Antiplatelet activity and TNF- release inhibition of phthalimide derivatives useful to treat sickle cell anemia. MEDICINAL CHEMISTRY RESEARCH, v. 28, n. 8, p. 1264-1271, . Web of Science Citations: 0. (15/19531-1, 13/23461-3)

SANTOS FERNANDES, GUILHERME FELIPE; BERNARDES SILVA, GABRIEL DALIO; PAVAN, ALINE RENATA; CHIBA, DIEGO EIDY; CHIN, CHUNG MAN; DOS SANTOS, JEAN LEANDRO. Epigenetic Regulatory Mechanisms Induced by Resveratrol. NUTRIENTS, v. 9, n. 11, . Web of Science Citations: 19. (15/19531-1, 16/08470-4, 16/08880-8, 16/09502-7)

LORENA BLAU; RENATO FARINA MENEGON; MAN CHIN CHUNG. Pró-fármaco ativado por enzima, uma estratégia promissora na quimioterapia. Química Nova, v. 29, n. 6, p. 1307-1317, . (01/01192-3)

YAMASAKI, PAULO RENATO; DO NASCIMENTO, DEJAIR CAETANO; CHELUCCI, RAFAEL CONSOLIN; FERNANDES BELONE, ANDREA DE FARIA; ROSA, PATRICIA SAMMARCO; DIORIO, SUZANA MADEIRA; FERREIRA DE MELO, THAIS REGINA; BARBIERI, KARINA PEREIRA; POLESI PLACERES, MARISA CAMPOS; CARLOS, IRACILDA ZEPONE; et al. Synthesis and evaluation of novel dapsone-thalidomide hybrids for the treatment of type 2 leprosy reactions. Bioorganic & Medicinal Chemistry Letters, v. 24, n. 14, p. 3084-3087, . Web of Science Citations: 6. (12/50359-2)

DOS SANTOS, JEAN LEANDRO; VARANDA, ELIANA A.; LIMA, LIDIA MOREIRA; CHIN, CHUNG MAN. Mutagenicity of New Lead Compounds to Treat Sickle Cell Disease Symptoms in a Salmonella/Microsome Assay. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 11, n. 2, p. 779-788, . Web of Science Citations: 8. (07/56115-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

GONCALVES, Regiane Rocha. Síntese de pró-fármaco antiinflamatório dirigido ao fígado, potencialmente ativo na inibição do granuloma periovular esquistossomótico.  79 f. Dissertação (Mestrado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciencias Farmaceuticas.  Araraquara.  (98/15469-2

BLAU, Lorena. Obtenção de pró-fármaco potencialmente antichagásico para uso em sistema ADEPT.  168 f. Dissertação (Mestrado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciencias Farmaceuticas.  Araraquara.  (03/04595-7

BOSQUESI, Priscila Longhin. Planejamento, sintese e avaliação biológica de derivados furoxânicos e benzofuroxânicos potencialmente antichagásicos. Tese (Doutorado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciencias Farmaceuticas.  (10/50330-9

CHIBA, Diego Eidy. Síntese e avaliação biológica de novos compostos das séries LAPDESF FUR-PQ E LAPDESF FUR-TS contra Trypanosoma cruzi.  141 f. Dissertação (Mestrado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciências Farmacêuticas.  (13/13172-4

MACHADO, Marcella Gabrielle Mendes. Síntese e avaliação anti-inflamatória de derivados esteroides da série Lapdesf GL-FT.  115 f. Tese (Doutorado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciências Farmacêuticas.  (14/08728-6

CHELUCCI, Rafael Consolin. Planejamento, síntese e avaliação farmacológica de híbridos com potencial atividade no tratamento da doença de Alzheimer.  233 f. Tese (Doutorado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciências Farmacêuticas.  (13/23461-3

BOSQUESI, Priscila Longhin. Avaliação da presença do grupo nitro na atividade antichagásica e mutagênica do candidato a fármaco hidroximetilnitrofural (NFOH).  104 f. Dissertação (Mestrado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciencias Farmaceuticas.  Araraquara.  (07/53160-4

SANTOS, Jean Leandro dos. Síntese e avaliação farmacológica de protótipos candidatos a fármacos para o tratamento dos sintomas da anemia falciforme.  129 f. Tese (Doutorado) -  Campus de Araraquara.  Universidade Estadual Paulista (UNESP).  Araraquara.  (07/56115-0

CHIBA, Diego Eidy. Planejamento, síntese e avaliação biológica de novos derivados da série LAPDESF FTD-AO com potencial atividade no tratamento da Doença de Alzheimer. Tese (Doutorado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciências Farmacêuticas.  (16/08470-4

YAMASAKI, Paulo Renato. Planejamento e síntese de pró-fármacos recíprocos uteis como filtros solares.  85 f. Dissertação (Mestrado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciências Farmacêuticas.  (10/03825-2

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