Abstract
Colorectal cancer (CCR) is one of the 10 most cancers worldwide, causing almost 10 million deaths in 2018. In Brazil, it is the third most incident cancer in men and the second, in women, reaching more than 16 thousand deaths in 2018. In the last 3 years it has been observed about 10% increase in mortality caused by CCR, demonstrating that the existing treatments are not totally effective…