graduation at Medicina from Universidade de São Paulo (2000), master's at Master in Science from Harvard School of Public Health (2013) and doctorate at Medicina (Patologia) from Universidade de São Paulo (2010). Has experience in Medicine, acting on the following subjects: idoso, artéria carótida, aterosclerose and pronto-socorro. (Source: Lattes Curriculum)
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The Brazilian population is aging at an accelerated pace, with the age group of individuals aged 90 and over showing the greatest proportional growth among older adults. This population has a high rate of chronic degenerative diseases, among which dementia stands out due to its high prevalence and morbidity and mortality. However, few studies on dementia have been carried out in older peo…
Brain aging is highly heterogeneous. "SuperAgers" are an example of individuals over the age of 80 years who have memories as sharp as healthy people 20 to 30 decades younger. General changes that occur during the aging process in brain volume, cortical density, white matter and neurotransmitter systems can play a role in cognitive and psychiatric symptoms, which have a huge impact in gl…
Alzheimer's disease (AD) is the main cause of dementia worldwide. The definitive diagnosis of DA is clinicopathological and based on amyloid ² (A²) plaques and neurofibrillary tangles. However, the link between amyloid cascade and depositions of phosphorylated tau (p-tau) is still missing. In this scenario, neuroinflammation appears to play an important role. Experimental models of AD hav…
Introduction: Coronary artery disease (CAD) is the main cause of morbimortality in the world. In a previous study, we found a positive correlation between the number of macrophages in the perivascular adipose tissue (PAT) and the percentage of obstruction of the atherosclerotic plaque,and an association between B-lymphocytes and unstable lesions. However, it is necessary toelucidate the i…
One of the main cause of morbidity and mortality in the world is coronary artery disease (CAD). Studies that investigate the pathophysiology of CAD are important to the prevention and treatment of this disease. The inflammation in epicardial adipose tissue (EAP) appears to be associated with CAD. However, the relation between the proximity of CAD and inflammation in EAP has not been eluci…
(Only some records are available in English at this moment)
Dementia is a syndrome that causes cognitive decline and affects an individual's functionality. Approximately 55 million people live with dementia worldwide, and it is expected that this number will triple in the next 50 years. Aging is known to be the greatest risk factor for dementia; however, recently, 12 modifiable risk factors have been identified, including low education, systemic a…
Carotid atherosclerosis has been associated with cerebrovascular lesions and vascular dementia in clinical and radiological studies. This project will investigate the association of atherosclerosis in carotid arteries evaluated by morphometric criteria with cerebrovascular diseases and vascular dementia, in a cross-sectional observational study with autopsy material. We will use samples c…
Background: Previous studies suggest an association between Alzheimer's Disease and thepresence of atherosclerosis in the carotid arteries. However, the association betweenatherosclerotic carotid plaque composition and the neuropathological lesions of Alzheimer'sdisease (neuritic plaques and neurofibrillary tangles) has not been explored yet. Objectives:Correlate the neuropathological les…
Introduction: Cardiovascular disease is the main cause of mortality worldwide, with coronary artery disease (DAC) being the most common among them. Atherosclerosis is a chronic inflammatory condition, being an autoimmune response to elevated LDL-cholesterol. Recent studies show differences in the levels of DAC incidence between women and men. The hormonal, behavioral, and lifestyle influe…
Alzheimer's Disease (AD) is a progressive neurodegenerative disease, being the most frequent cause of dementia worldwide. Around 50 million people is estimated to have AD or other dementias and this number tends to double every 20 years. Although the etiology of the disease is partially explained by the deposition of aggregated forms of ²-amyloid proteins and neurofibrillary tangles in th…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 4 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 7 / 7 | Completed scholarships in Brazil |
| 15 / 15 | All research grants and scholarships |
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CV Lattes
ORCID