Fernando Gomes
CV Lattes
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Universidade de São Paulo (USP). Instituto de Biociências (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Licenciatura em Ciências Biológicas from Universidade Estadual de Ponta Grossa (2009), master's at Microbiology from Universidade de São Paulo (2012) and doctorate at Genetics from Universidade de São Paulo (2016). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms, acting on the following subjects: reparo de dna, herbaspirillum seropedicae and reca. (Source: Lattes Curriculum)
- Importing of peroxiredoxins to distinct mitochondrial compartments: impacts on physiology and pathology, BP.PD
Abstract
Human mitochondria contain approximately 1500 different proteins, most of which (99%) are synthesized on cytosolic ribosomes, and subsequently imported to their functional destination in the mitochondrial subcompartments by specific targeting signals. Presequence is a sorting signal in the form of an N-terminal extension that directs the import of nearly all mitochondrial matrix protein...
- Functional characterization of mitochondrial peroxiredoxin (Prx1p) in the redox physiology of Saccharomyces Cerevisiae, BP.DR
Abstract
Thiol-dependent peroxidases, as peroxiredoxins, play a role in the response of oxidative stress due to reactive oxygen species (ROS) accumulation. There are five isoforms of peroxiredoxins in Saccharomyces cerevisiae, localized in different cellular compartments. Prx1p is a mitochondrial isoform and plays an important role in the elimination of hydrogen peroxide produced during the elec...
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| 1 / 1 | Completed scholarships in Brazil |
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(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
GOMES, FERNANDO; PALMA, FLAVIO ROMERO; BARROS, MARIO H.; TSUCHIDA, EDUARDO T.; TURANO, HELENA G.; ALEGRIA, THIAGO G. P.; DEMASI, MARILENE; NETTO, LUIS E. S.. Proteolytic cleavage by the inner membrane peptidase (IMP) complex or Oct1 peptidase controls the localization of the yeast peroxiredoxin Prx1 to distinct mitochondrial compartments. Journal of Biological Chemistry, v. 292, n. 41, p. 17011-17024, OCT 13 2017. Web of Science Citations: 4. (13/07937-8, 12/21722-1, 08/07971-3)
(References retrieved automatically from State of São Paulo Research Institutions)
GOMES, Fernando. Caracterização funcional da peroxirredoxina mitocondrial (Prx1) na fisiologia redox de Saccharomyces cerevisiae. 2016. Tese (Doutorado) – Instituto de Biociências. Universidade de São Paulo (USP). São Paulo. (13/04240-6)