Pharmacy degree from Universidade de São Paulo (1990) and Ph.D. in Chemistry from Universidade Federal de São Carlos (1997). Pos-doctoral fellow at USP (1996-1997) and Harvard Medical School (2006-2007). Professor of Medicinal Chemistry and Natural Products at Pharmacy School at Ribeirao Preto, Universidade de Sao Paulo (FCFRP-USP), since 1998. In 2009 was promoted to Associate Professor position and in 2019 to Full Professor. She served as Associate editor of Journal of the Brazilian Chemical Society, Scientific Reports, mSystems and guest editorial member of Frontiers in Microbiology and Annual Review of Microbiology. Currently she is part of the Editorial Board of Brazilian Journal of Pharmacognosy. She has coordinated the first ICBG in Brazil, together with Jon Clardy. This initiative was supported by the FIC-NIH and FAPESP (2014-2020). She served as president of Graduate Studies Committee (CPG) at FCFRP-USP during 2018-2022. Currently, she is Deputy Director of FCFRP-USP (2022-2026). She has experience in the Chemistry of Natural Products, with emphasis in the following subjects: symbiont microorganisms, natural products, chemical ecology of interspecies interactions. http://pupolab.fcfrp.usp.br/ Instagram: @PupoLab.LQMo (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
The lack of robustly validated drug targets has proved a significant barrier to the discovery of new treatments for visceral leishmaniasis and Chagas' disease. Furthermore, target deconvolution studies with active leads emerging from current small molecule phenotypic screening have confirmed that the same relatively few molecular targets are being hit repeatedly. This project aims to ad…
Modern tools have enabled a revolution in the derivation of therapeutic products from the study of metabolic symbionts. Some of the most complex and promising metabolic symbionts belong to the insect order Hemiptera which include successful plant-pests (e.g. aphids, etc.) and human blood-feeders (e.g. kissing bugs - the Chagas vector). The most complex Hemipteran symbiosis occurs in the i…
An International Cooperative Biodiversity Group (ICBG) with an interdisciplinary leadership team of physicians, pharmacologists, evolutionary biologists, and chemists will discover and develop therapeutic agents produced by Brazilian symbiotic bacteria. The team will target three therapeutic areas: 1) infectious fungal pathogens, 2) Chagas disease and leishmaniasis, and 3), cancers of the…
(Only some records are available in English at this moment)
Several yeasts live in association with insects. Although some models have been deeply studied, such as Drosophila-yeast associations, some interactions are still elusive, like the stingless bees (Hymenoptera: Apoidea: Apidae: Meliponini). The project aims to describe the diversity of yeasts associated with Meliponini bees (using the bees Scaptotrigona depilis and Tetragona clavipes as a …
The search for new antimicrobial compounds has become increasingly important for the therapeutic arsenal due to the increase of resistant microorganisms. Soil, in particular Brazilian soil, represents a promising and little explored source of microorganisms that produce these compounds. Therefore, the present project proposes the chemical analysis of two bacterial strains, isolated from t…
Natural products, which are derived from plants, marine organisms, and microorganisms, are crucial for the development of new pharmaceuticals. It is estimated that approximately half of the pharmaceuticals sold originate from natural products. Microorganisms are important sources in the discovery of new pharmaceuticals, with antimicrobial and antitumor potential, among others. Furthermore…
(Only some records are available in English at this moment)
Natural products play an important role in the discovery of bioactive compounds, helping in the process of developing new drugs. In this context, microorganisms have a remarkable contribution, since many bioactive compounds are biosynthesized by them. It is known that throughout evolution social insects have established symbiotic relationships with microorganisms, these relationships are …
Neglected Tropical Diseases (NTDs) are a set of diseases strongly present in developing countries, with precarious access to health and basic sanitation systems, prevalent in tropical and subtropical regions. Although there are programs for the prevention and eradication of NTDs, such as Chagas Disease and Leishmaniasis, few drugs are available for treatment, with relevant adverse reactio…
Attine ants have as a behavioral feature, the cultivation of "fungal gardens" for nutritional purposes. However, the integrity of the colonies can be compromised when the growth of Escovopsis fungus is observed, which is a specialized parasite of these gardens. One of the strategies to protect colonies is the establishment of a symbiotic relationship with actinobacteria, mainly of the gen…
(Only some records are available in English at this moment)
Trypanosomiasis (Chagas disease and Human African trypanosomiasis -HAT) are the most serious of tropical neglected diseases, affecting 6 to 7 million people in poverty conditions in Latin America and endemic in 36 sub-Saharan Africa countries. Chagas disease and HAT are caused by protozoan parasites from the genus Trypanosoma whose vectors are Triatominae (kissing bugs) in Latin America a…
The ants of the Attini tribe have developed over time a relationship of domestication and later mutualism with Basidiomycete fungi, which are grown in fungal gardens and serve as the main food source of these ants. Several microorganisms can parasitize the colonies of these farmer insects, and the ants have created physical and chemical defense mechanisms against these invaders. However, …
Microorganisms associated with social insects have been extensively studied as sources of new chemical structures with antimicrobial activity; however, there are no reports in the literature about the secondary metabolites produced by microorganisms associated with the Cecropia-Azteca interaction. In an ongoing PhD project, seven strains of actinobacteria were isolated from Cecropia-Aztec…
(Only some records are available in English at this moment)
| 11 / 7 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 57 / 43 | Completed scholarships in Brazil |
| 10 / 10 | Completed scholarships abroad |
| 82 / 64 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID