Abstract
The epithelial-mesenchymal transition process (EMT) in urogenital carcinomas correlates with tumor growth and metastasis. In this process, the cells express mesenchymal markers such as vimentin, acquiring a fusiform phenotype that improves tumoral invasion. The EMT is controlled by specific factors as TGF- ²1 (transforming growth factor-beta). The indoleamine 2,3 dioxygenase (IDO) enzyme …