Juliano Coelho da SIlveira
CV Lattes
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Universidade de São Paulo (USP). Faculdade de Zootecnia e Engenharia de Alimentos (FZEA) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Pontifícia Universidade Católica do Rio Grande do Sul (2004) and master's at Genética e Toxicologia Aplicada from Universidade Luterana do Brasil (2007). Has experience in Genetics, focusing on Genetics, acting on the following subjects: toxicologia, genética, marcadores moleculares, biomonitoramento and teste cometa. (Source: Lattes Curriculum)
- Cell-secreted vesicles containing miRNAs modulate epigenetic changes during in vitro culture of bovine gametes and embryos, AP.JP
Abstract
The use of assisted reproduction techniques presents an alternative to solve reproductive problems in domestic species and humans. However, there is concern that epigenetic changes occurring during in vitro culture adversely affect tissue programing during fetal development and could lead to a higher pre-disposition to develop heart diseases, reproductive problems, and development of tu...
- Validation of miRNAs targets through luciferase assay in bovine granulosa cells, AV.EXT
Abstract
MicroRNAs (miRNAs) are small noncoding RNAs involved in modulate mRNA levels by repression or degradation. MiRNAs are found in body fluids enclosed in extracellular vesicles. Recently, miRNAs studies demonstrated the importance of these molecules regulating target genes and biological pathways. Besides, extracellular vesicles containing miRNAs are potential biomarkers and tools for diff...
- Niamh Forde | University of Leeds - Inglaterra, AV.EXT
Abstract
The majority of reproductive wastage occurs in the first 2-3 weeks of pregnancy. Establishing successful early pregnancy requires communication between the gametes and the maternal environrnent as well as successful bi-directional communication between the developing conceptus (embryo proper and extra-embryonic membranes) and the uterine environment. Recently, extracellular vesicles (EV...
- Multi-user equipment approved in grant 2014/22887-0: Nanosight LM10, AP.EMU
Abstract
The use of assisted reproduction techniques presents an alternative to solve reproductive problems in domestic species and humans. However, there is concern that epigenetic changes occurring during in vitro culture adversely affect tissue programing during fetal development and could lead to a higher pre-disposition to develop heart diseases, reproductive problems, and development of tu...
- Effects of extracellular vesicle supplementation during bovine embryo cleavage, BP.MS
Abstract
The use of assisted reproduction techniques is an alternative to solve reproductive problems in domestic species and in humans. However, there is concern that the in vitro culture of gametes and embryos can generate epigenetic changes which may lead to increased pre-disposition to cardiac, reproductive or tumor development in adult life. Epigenetic changes are regulated by DNA methylati...
- New method to evaluate intercellular communication mediated by extracellular vesicles within the bovine ovarian follicle, BP.IC
Abstract
Numerous studies have now been performed to optmize assisted reproduction techniques. The efficiency of the in vitro embryo production is dependent on intercellular communication, and this communication can be mediated by extracellular vesicles (microvesicles and exosomes), which can be secreted and incorporated by different cell types. In this way, new tools to determine the role of ex...
- Description of a new mechanism involved in cellular communication between female reproductive system cells and oocyte mediated by extracellular vesicles and their impacts on oocyte maturation, fertilization and bovine embryo cleavage, BP.MS
Abstract
The use of assisted reproduction techniques is an alternative to solve reproductive problems in domestic species and in humans. However, there is concern that the in vitro culture of gametes and embryos can cause epigenetics changes, which may lead to increased predisposition to cardiac and reproductive diseases as well as tumor development in adult life. Epigenetics changes are regulat...
- Dynamics of RNA expression and epigenetic changes during bovine oocyte maturation and embryonic development: comparing in vivo and in vitro systems, BP.IC
Abstract
Assisted reproductive technologies are an alternative to solve reproductive problems in domestic animals and humans. However, there is a concern that in vitro culture of gametes and embryos could generate epigenetic changes, which may lead to a higher predisposition to health problems in adulthood. Epigenetic changes are regulated by DNA methylation, by post-translational modifications ...
(Only some records are available in English at this moment)
- The role of extracellular vesicles in the intercellular communication within the bovine cumulus-oocyte complex during in vitro maturation, BE.EP.MS
Abstract
Assisted reproductive techniques (ART) are alternatives to infertility and to increase the production of domestic animals. Although these techniques are widely used, they can cause negative consequences since early pregnancy until adult life. Attempts to mimic in vivo environment are applied to improve problems caused by ARTs. Extracellular vesicles (EVs) secreted by cells are important...
| 1 / 1 | Ongoing research grants |
| 3 / 3 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 5 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 11 / 11 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 15 |
| Citations | 69 |
| Cit./Article | 4.6 |
| Data from Web of Science | |
ANDRADE, GABRIELLA MAMEDE; DA SILVEIRA, JULIANO COELHO; PERRINI, CLAUDIA; DEL COLLADO, MAITE; GEBREMEDHN, SAMUEL; TESFAYE, DAWIT; MEIRELLES, FLAVIO VIEIRA; PERECIN, FELIPE. The role of the PI3K-Akt signaling pathway in the developmental competence of bovine oocytes. PLoS One, v. 12, n. 9, SEP 18 2017. Web of Science Citations: 10. (14/22887-0, 14/21034-3, 12/50533-2, 13/08135-2)
DA SILVEIRA, JULIANO C.; DE ANDRADE, GABRIELLA M.; NOGUEIRA, MARCELO F. G.; MEIRELLES, FLAVIO V.; PERECIN, FELIPE. Involvement of miRNAs and Cell-Secreted Vesicles in Mammalian Ovarian Antral Follicle Development. REPRODUCTIVE SCIENCES, v. 22, n. 12, p. 1474-1483, DEC 2015. Web of Science Citations: 12. (13/10473-3, 12/50533-2, 13/08135-2)
DEL COLLADO, MAITE; DA SILVEIRA, JULIANO COELHO; SANGALLI, JULIANO RODRIGUES; ANDRADE, GABRIELLA MAMEDE; DA SILVA SOUSA, LETICIA RABELLO; SILVA, LUCIANO ANDRADE; MEIRELLES, FLAVIO VIEIRA; PERECIN, FELIPE. Fatty Acid Binding Protein 3 And Transzonal Projections Are Involved In Lipid Accumulation During In Vitro Maturation Of Bovine Oocytes. SCIENTIFIC REPORTS, v. 7, JUN 1 2017. Web of Science Citations: 12. (14/21034-3, 15/26056-8, 14/22887-0, 14/03281-3, 13/08135-2)
DA SILVEIRA, JULIANO C.; DE AVILA, ANA CLARA F. C. M.; GARRETT, HANNAH L.; BRUEMMER, JASON E.; WINGER, QUINTON A.; BOUMA, GERRIT J.. Cell-secreted vesicles containing microRNAs as regulators of gamete maturation. Journal of Endocrinology, v. 236, n. 1, p. R15-R27, JAN 2018. Web of Science Citations: 10. (17/02037-0, 15/16985-1, 13/10473-3, 12/50533-2, 14/22887-0)
DA SILVEIRA, JULIANO C.; ANDRADE, GABRIELLA M.; DEL COLLADO, MAITE; SAMPAIO, RAFAEL V.; SANGALLI, JULIANO R.; SILVA, LUCIANO A.; PINAFFI, FABIO V. L.; JARDIM, IZABELLE B.; CESAR, MARCELO C.; NOGUEIRA, MARCELO F. G.; et al. Supplementation with small-extracellular vesicles from ovarian follicular fluid during in vitro production modulates bovine embryo development. PLoS One, v. 12, n. 6, JUN 15 2017. Web of Science Citations: 8. (13/10473-3, 14/21034-3, 12/50533-2, 14/22887-0, 13/08135-2)
DE BEM, T. H. C.; DA SILVEIRA, J. C.; SAMPAIO, R. V.; SANGALLI, J. R.; OLIVEIRA, M. L. F.; FERREIRA, R. M.; SILVA, L. A.; PERECIN, F.; KING, W. A.; MEIRELLES, F. V.; et al. Low levels of exosomal-miRNAs in maternal blood are associated with early pregnancy loss in cloned cattle. SCIENTIFIC REPORTS, v. 7, OCT 30 2017. Web of Science Citations: 3. (14/22887-0, 12/50533-2, 13/08135-2)
ANDRADE, G. M.; MEIRELLES, F. V.; PERECIN, F.; DA SILVEIRA, J. C.. Cellular and extracellular vesicular origins of miRNAs within the bovine ovarian follicle. REPRODUCTION IN DOMESTIC ANIMALS, v. 52, n. 6, p. 1036-1045, DEC 2017. Web of Science Citations: 6. (14/21034-3, 13/10473-3, 12/50533-2, 14/22887-0, 13/08135-2)
DEL COLLADO, MAITE; ANDRADE, GABRIELLA MAMEDE; MEIRELLES, FLAVIO VIEIRA; DA SILVEIRA, JULIANO COELHO; PERECIN, FELIPE. Contributions from the ovarian follicular environment to oocyte function. ANIMAL REPRODUCTION, v. 15, n. 3, p. 261-270, JUL-SEP 2018. Web of Science Citations: 0. (18/01431-9, 13/08135-2, 14/21034-3, 14/22887-0, 17/19825-0)
SANTOS, G.; BOTTINO, M. P.; SANTOS, A. P. C.; SIMOES, L. M. S.; SOUZA, J. C.; FERREIRA, M. B. D.; DA SILVEIRA, J. C.; AVILA, A. C. F. C. M.; BRIDE, A.; SALES, J. N. S.. Subclinical mastitis interferes with ovulation, oocyte and granulosa cell quality in dairy cows. Theriogenology, v. 119, p. 214-219, OCT 1 2018. Web of Science Citations: 0. (14/22887-0, 15/21829-9)
SANGALLI, JULIANO RODRIGUES; SAMPAIO, RAFAEL VILAR; DEL COLLADO, MAITE; DA SILVEIRA, JULIANO COELHO; CAMARA DE BEM, TIAGO HENRIQUE; PERECIN, FELIPE; SMITH, LAWRENCE CHARLES; MEIRELLES, FLAVIO VIEIRA. Metabolic gene expression and epigenetic effects of the ketone body beta-hydroxybutyrate. SCIENTIFIC REPORTS, v. 8, SEP 13 2018. Web of Science Citations: 1. (14/22887-0, 16/13416-9, 14/21097-5, 13/06673-7, 13/08135-2, 14/21034-3, 12/50533-2)
OTAGUIRI, KATIA KAORI; DOS SANTOS, DAIANE FERNANDA; SLAVOV, SVETOSLAV NANEV; DEPIERI, LIVIA VIEIRA; BONINI PALMA, PATRICIA VIANNA; MEIRELLES, FLAVIO VIEIRA; COVAS, DIMAS TADEU; DA SILVEIRA, JULIANO COELHO; KASHIMA, SIMONE. TAX-mRNA-Carrying Exosomes from Human T Cell Lymphotropic Virus Type 1-Infected Cells Can Induce Interferon-Gamma Production In Vitro. AIDS Research and Human Retroviruses, v. 34, n. 12, NOV 2018. Web of Science Citations: 0. (15/16985-1, 14/22887-0)
SANTOS ROBALLO, KELLY CRISTINE; DA SILVEIRA, JULIANO COELHO; BRESSAN, FABIANA FERNANDES; DE SOUZA, ALINE FERNANDA; PEREIRA, VITORIA MATTOS; PINZON PORRAS, JORGE ELIECER; ROS, FELIPE AUGUSTO; PULZ, LIDIA HILDEBRAND; STREFEZZI, RICARDO DE FRANCISCO; MARTINS, DANIELE DOS SANTOS; et al. Neurons-derived extracellular vesicles promote neural differentiation of ADSCs: a model to prevent peripheral nerve degeneration. SCIENTIFIC REPORTS, v. 9, AUG 1 2019. Web of Science Citations: 0. (15/17897-9, 14/22887-0, 15/21829-9, 13/08135-2)
DE FIGUEIREDO PESSOA, LAIS VICARI; LISBOA PIRES, PEDRO RATTO; DEL COLLADO, MAITE; GODOY PIERI, NAIRA CAROLINE; RECCHIA, KAIANA; SOUZA, ALINE FERNANDA; PERECIN, FELIPE; DA SILVEIRA, JULIANO COELHO; CESAR DE ANDRADE, ANDRE FURUGEN; AMBROSIO, CARLOS EDUARDO; et al. Generation and miRNA Characterization of Equine Induced Pluripotent Stem Cells Derived from Fetal and Adult Multipotent Tissues. STEM CELLS INTERNATIONAL, 2019. Web of Science Citations: 0. (12/50533-2, 13/17955-3, 08/57877-3, 15/26818-5, 14/22887-0, 13/08135-2)
DEL COLLADO, MAITE; DA SILVEIRA, JULIANO C.; OLIVEIRA, MARCELO L. F.; ALVES, BARBARA M. S. M.; SIMAS, ROSINEIDE C.; GODOY, ADRIANA T.; COELHO, MIRELA B.; MARQUES, LYGIA A.; CARRIERO, MATEUS M.; NOGUEIRA, MARCELO F. G.; et al. In vitro maturation impacts cumulus-oocyte complex metabolism and stress in cattle. Reproduction, v. 154, n. 6, p. 881-893, DEC 2017. Web of Science Citations: 3. (14/22887-0, 14/21034-3, 12/50533-2, 14/03281-3, 13/08135-2)
BOMFIM, MONALISA M.; ANDRADE, GABRIELLA M.; DEL COLLADO, MAITE; SANGALLI, JULIANO R.; FONTES, PATRICIA K.; NOGUEIRA, MARCELO F. G.; MEIRELLES, FLAVIO V.; DA SILVEIRA, JULIANO C.; PERECIN, FELIPE. Antioxidant responses and deregulation of epigenetic writers and erasers link oxidative stress and DNA methylation in bovine blastocysts. Molecular Reproduction and Development, v. 84, n. 12, p. 1296-1305, DEC 2017. Web of Science Citations: 4. (14/21034-3, 14/22887-0, 12/50533-2, 14/21042-6, 13/08135-2)