Abstract
Adrenocortical cancer accounts for 0.05-0.2% of all cancers, with an estimated incidence of 0.5-2.0/million/year in adults. Interestingly, the incidence of pediatric adrenocortical tumors is remarkably high in South and Southern Brazil, where it is estimated to be 10-15 times greater than the worldwide incidence. There are currently few therapeutic options for patients with adrenocortical…