CNPq Level II Productivity Scholarship. She holds a degree in Biochemical Pharmacy from the Federal University of Goiás (1997), a Master's degree in Tropical Medicine from the Federal University of Goiás (2001) and a PhD in Microbiology and Immunology from the Federal University of São Paulo (2005). She is currently the Coordinator of the Hcor Biobank (Syrian Charitable Association), a Researcher at the Amaral Carvalho Hospital (Jaú) and a Permanent Professor of the Postgraduate Programs in Pharmacology and Medicine (Gynecology) at the Federal University of São Paulo (UNIFESP). She has been working with Circulating Tumor Cells, one of the compartments of Liquid Biopsy, since 2011, with experience in both solid tumors and sarcomas and desmoid tumors. She also has experience in the area of #8203;#8203;Immunology. It recently received the ICPerMed Best Practice Recognition award as the best project in Latin America in Personalized Medicine (PM). (Source: Lattes Curriculum)
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Venous thromboembolism (VTE) is a common complication in patients with active cancer. Patients with cancer have a 4 to 7 times higher risk of developing VTE compared to the general population. VTE is associated with an annual recurrence rate of 21% and a bleeding risk of 12%. This often leads to the need for prolonged anticoagulation therapy and interruption of chemotherapy. Chemotherapy …
The main reason of cancer-related mortality is the spread of cancer cells to distant sites (micrometastases). However, only a few small groups of tumor cells can metastasize by acquiring mechanism to decrease the immune response. Changes in the systemic inflammatory response to the tumor can be measured by blood-based parameters. In particular, the proportion of neutrophiles- lymphocytes …
Head and neck cancer represents 6% of new cancer cases diagnosed annually, accounting for 650,000 new cases around the world. Its management is multidisciplinary and despite all efforts, about 50% of patients show disease recurrence.The spread of cancer requires the presence of circulating tumor cells (CTCs), which are rare cells surrounded by billions of hematopoietic cells.There are som…
Immunotherapy has provided beneficial results for cancer patients. Recently, the ANVISA, based on the KEYNOTE-355 study, approved the use of the immune checkpoint inhibitor (ICI) pembrolizumab plus chemotherapy for patients with unresectable locally recurrent or metastatic triple-negative breast cancer, with PD-L1 expression e 10. Although the results are encouraging, evidence suggests th…
Ovarian Cancer is one of the Cancers with higher mortality in women, especially among the periods of menopause/postmenopause. Its characterization is important for diagnosis/specific treatments. Regardless of therapeutic advances, most patients succumb to the disease. Mutations of the BRCA1 or BRCA2 genes can lead to resistance to platinum-based chemotherapy. A new type of therapeutic app…
Renal carcinoma represents one of the 10 most common cancers in the world and it is part of a heterogeneous group whose one of the main histological variants is the clear cell renal cell carcinoma (CRCC). Few methodologies are available for the early detection of this neoplasm. Due to the tumor heterogeneity, several studies have been carried out for the molecular characterization, throug…
Circulating Tumor Cells (CTCs) are rare cells that detach from some tumor site, invade blood vessels, being able to achieve new sites to form single or multiple micrometastasis. Desmoid tumor, also known as aggressive fibromatosis, is a rare, locally invasive, and non-metastasizing type of cancer. Soft tissue and bone sarcomas include a large group of several heterogeneous subtypes of mes…
Cancer has become a major public health problem in developed and developing countries, accounting for more than six million cases of deaths each year, accounting for about 12% of all causes of death in the world. Anal cancer accounts for 4% of all malignant neoplasms of the lower digestive tract and has one of the etiologic factors, the human papillomavirus (HPV), which gives it a strong …
(Only some records are available in English at this moment)
Understanding the complex behavior of immune system cells, such as B lymphocytes and T lymphocytes, in responding to cancerous growth is of central importance to cancer treatment. Natural phenomena, specifically trogocytosis and cell fusion, can lead to the development of metastases by acquiring characteristics such as genetic and epigenetic heterogeneity, chemotherapeutic resistance and …
| 3 / 3 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 7 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 13 / 13 | All research grants and scholarships |
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CV Lattes
ORCID