graduation at Medicina from Universidade Estadual Paulista Júlio de Mesquita Filho (2005) and doctorate at Fisiopatologia em Clínica Médica from Faculdade de Medicina de Botucatu (2011). Has experience in Medicine, focusing on Medicine, acting on the following subjects: clínica médica, doxorrubicina, emergências clínicas, cardiotoxicidade and insuficiencia cardíaca. (Source: Lattes Curriculum)
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Doxorubicin is a chemotherapeutic drug use in the treatment of malignant neoplasms. It is highly effective; however, it can cause cardiotoxicity, the most serious side effect of doxorubicin treatment. Chronic cardiotoxicity manifests as left ventricular dilation and cardiac dysfunction, which increases the mortality of these patients and worsens the quality of life. The pathophysiology of…
Doxorubicin (DOX) is a drug used in the treatment of malignancies, but cardiotoxicity is the major side effect, which can be initiated immediately after drug´s infusion. Mechanisms involved in the genesis of the injury are increased inflammatory activity and activation of matrix metalloproteinases (MMP). Interventions which minimize activation of MMPs may play a role in cardiotoxicity's p…
Doxorubicin (DOX) is one of most eficcient antineoplastic, widely used as an anti-tumor drug in many chemotherapic treatment regimens. Although it is substantial therapeutic potential, DOX induces several side effects. The genesis of side effects is mainly due to the production of reactive oxygen species. Thus the suplemmentation of orange juice whose is known for it is antioxidant potent…
Cardiotoxicity is the major side effect of doxorubicin treatment. The identification of mechanisms involved in pathophysiology of cardiotoxicity allows the discovery news strategies to attenuate this complication. Ceramide is formed by the metabolism of membrane cell phospholipids and participates in intracellular signaling and modulates pathological pathways. Supplementation of omega 3 c…
Coronary artery disease is one of the major causes of death in the world, and coronary artery bypass grafting (CABG) is an important treatment strategy. The majority of CABGs use cardiopulmonary bypass (CPB), which improves the technical quality of the surgery, but increase the risk of complications, such as acute kidney injury (AKI) that can occur in 30% of the patients. AKI is associate…
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| 3 / 2 | Completed research grants |
| 5 / 5 | Completed scholarships in Brazil |
| 8 / 7 | All research grants and scholarships |
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CV Lattes
ORCID