Abstract
The inflamassomes are protein complexes of high molecular weight formed after recognition of pathogens or damage signals (DAMPs) in the cellular cytosol. After activation, the inflamassomes activate caspase-1 and caspase-1, mediates the processing and secretion of the cytokines IL-1beta and IL-18 and also cell death by pyroptosis. More recently, new effector functions have been assigned t…