graduate at Medicina from Pontifícia Universidade Católica de Campinas (1982), master's at Physiology from Universidade de São Paulo (1989) and ph.d. at Endocrinology from Universidade de São Paulo (1994). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: triiodotironina, tireoide, obesidade, biologia molecular and estrogeno. (Source: Lattes Curriculum)
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The thyroid hormone is widely involved in metabolic control processes, from fetal development to adulthood. Environmental disruptors in the gestational period, which could affect epigenetic control-ling processes, may predispose the susceptibility to metabolic diseases in adult life, like diabetes mellitus type 2. Although many studies have been associated with a reduction in Dio3 mRNA ex…
The UPEA (Research Unit for Animal Experimentation) is a building for keeping animals of experimental which was built with FINEP resources (UPEA - FINEP - Cross Action Pro-Infrastructure 2008 of R $ 1,577,949.00) and counterparts of the institution which have already reached R $ 500.000,00.A UPEA was designed as a research hub in animal experiments with ambient divided in contaminated and…
The bone tissue is extremely complex and is regulated by systemic and local factors. It presents considerable metabolic activity including the removal of mineralized bone through the osteoclasts followed by the formation of bone matrix by the osteoblasts. The association of T3 and E2 might lead to a complex response to the bone tissue activity and T3 produces effects upon bone resorption …
(Only some records are available in English at this moment)
White Adipose Tissue (TAB) is an important endocrine organ, essential for metabolic regulation of the organism, through adipokine production and secretion, such as adiponectin and leptin. It is known that TAB expresses receptors of the purinergic system, which are important in lipid metabolism, and can be activated by adenosine triphosphate (ATP) and its derivatives. In addition, TAB is m…
Thyroid hormones (HT), thyroxine (T4) and triiodothyronine (T3) are involved in the regulation of energy expenditure and thermogenesis, but alteration in HT levels is often associated with changes in body weight. The change in body weight is related to increased oxidative stress, which is a manifestation of metabolic imbalance related to obesity. A primary intracellular target for oxidati…
Thyroid Hormone (TH) accomplishes a crucial role in thorough placental and fetal development. However, transplacental transport of HT involves the integration between many mechanisms that have not been fully elucidated. Increasingly, researchers have been described the importance of the intrauterine environment and the involvement of mild maternal thyroid abnormalities with epigenetic fai…
(Only some records are available in English at this moment)
Adipose tissue (TA) is divided into white adipose tissue (TAB) and brown adipose tissue (TAM). TAB has a large lipid accumulation, whereas TAM has less lipid accumulation and a large number of mitochondria, presenting as a marker the mitochondrial uncoupling protein-1 (UCP-1). It is known that TAB can be converted to TAM, a process known as browning. TAB expresses purinergic system recept…
| 21 / 11 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 42 / 12 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 65 / 25 | All research grants and scholarships |
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CV Lattes
ORCID