CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Medicina (FMB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Medicina from Pontifícia Universidade Católica de Campinas (1982), master's at Physiology from Universidade de São Paulo (1989) and ph.d. at Endocrinology from Universidade de São Paulo (1994). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: triiodotironina, tireoide, obesidade, biologia molecular and estrogeno. (Source: Lattes Curriculum)
The thyroid hormone is widely involved in metabolic control processes, from fetal development to adulthood. Environmental disruptors in the gestational period, which could affect epigenetic control-ling processes, may predispose the susceptibility to metabolic diseases in adult life, like diabetes mellitus type 2. Although many studies have been associated with a reduction in Dio3 mRNA ...
The UPEA (Research Unit for Animal Experimentation) is a building for keeping animals of experimental which was built with FINEP resources (UPEA - FINEP - Cross Action Pro-Infrastructure 2008 of R $ 1,577,949.00) and counterparts of the institution which have already reached R $ 500.000,00.A UPEA was designed as a research hub in animal experiments with ambient divided in contaminated a...
The bone tissue is extremely complex and is regulated by systemic and local factors. It presents considerable metabolic activity including the removal of mineralized bone through the osteoclasts followed by the formation of bone matrix by the osteoblasts. The association of T3 and E2 might lead to a complex response to the bone tissue activity and T3 produces effects upon bone resorptio...
Upgrade the equipment of multi-user laboratories of Block 5 UNIPEX of the Botucatu Medical School and raising the quality and quantity of the results obtained in the experimental and translational research. Allow a greater number of researchers can use the multiuser area of Block 5 of UNIPEX. Increase the number of publications in journals indexed by the speed in obtaining results and i...
(Only some records are available in English at this moment)
Thyroid hormones (HT), thyroxine (T4) and triiodothyronine (T3) are involved in the regulation of energy expenditure and thermogenesis, but alteration in HT levels is often associated with changes in body weight. The change in body weight is related to increased oxidative stress, which is a manifestation of metabolic imbalance related to obesity. A primary intracellular target for oxida...
Thyroid Hormone (TH) accomplishes a crucial role in thorough placental and fetal development. However, transplacental transport of HT involves the integration between many mechanisms that have not been fully elucidated. Increasingly, researchers have been described the importance of the intrauterine environment and the involvement of mild maternal thyroid abnormalities with epigenetic f...
Breast cancer (BC) is one of the highest incidences among women and the highest mortality. Among BC variants, there are dependent hormones, in which estrogen (E2) on the estrogen receptor (ER) is well established in relation to BC progression. Although controversial, clinical studies show that there is a worse prognosis of BC when associated with thyroid pathology, especially hyperthyro...
The bone tissue is extremely complex and is regulated by systemic and local factors. It presents considerable metabolic activity including the removal of mineralized bone through the osteoclasts followed by the formation of bone matrix by the osteoblasts. The T3 might lead to a complex response to the bone tissue activity and produces effects upon bone resorption as well as bone formati...
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 20 / 10 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 39 / 9 | Completed scholarships in Brazil |
| 63 / 23 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 15 |
| Citations | 73 |
| Cit./Article | 4.9 |
| Data from Web of Science | |
CASTRO OLIMPIO, REGIANE MARQUES; FONTES MORETTO, FERNANDA CRISTINA; DE SIBIO, MARIA TERESA; DE OLIVEIRA, MIRIANE; MATHIAS, LUCAS SOLLA; GONCALVES, BIANCA MARIANI; DEPRA, IGOR CARVALHO; TILLI, HELENA PAIM.; RODRIGUES, BRUNA MORETTO; SARAIVA, PATRICIA PINTO; et al. The importance of estrogen for bone protection in experimental hyperthyroidism in human osteoblasts. Life Sciences, v. 231, AUG 15 2019. Web of Science Citations: 0. (14/16406-9)
TABATA M. SILVA; FERNANDA C. F. MORETTO; MARIA T. DE SIBIO; BIANCA M. GONÇALVES; MIRIANE OLIVEIRA; REGIANE M. C. OLIMPIO; DIEGO A. M. OLIVEIRA; SARAH M. B. COSTA; IGOR C. DEPRÁ; VICKELINE NAMBA; et al. Triiodothyronine (T3) upregulates the expression of proto-oncogene TGFA independent of MAPK/ERK pathway activation in the human breast adenocarcinoma cell line, MCF7. ARCHIVES OF ENDOCRINOLOGY METABOLISM, v. 63, n. 2, p. 142-147, Abr. 2019. (15/09686-8, 14/15209-5, 13/05629-4)
DE OLIVEIRA, MIRIANE; MELO LUVIZOTTO, RENATA DE AZEVEDO; CASTRO OLIMPIO, REGIANE MARQUES; DE SIBIO, MARIA TERESA; CONDE, SANDRO JOSE; RODRIGUES SILVA, CAROLINA BIZ; FONTES MORETTO, FERNANDA CRISTINA; NOGUEIRA, CELIA REGINA. Triiodothyronine Increases mRNA and Protein Leptin Levels in Short Time in 3T3-L1 Adipocytes by PI3K Pathway Activation. PLoS One, v. 8, n. 9, SEP 18 2013. Web of Science Citations: 10. (10/16911-4)
DE OLIVEIRA, MIRIANE; RODRIGUES, BRUNA MORETTO; CASTRO OLIMPIO, REGIANE MARQUES; MATHIAS, LUCAS SOLLA; DE SIBIO, MARIA TERESA; FONTES MORETTO, FERNANDA CRISTINA; GRACELI, JONES BERNARDES; NOGUEIRA, CELIA REGINA. Adiponectin and Serine/Threonine Kinase Akt Modulation by Triiodothyronine and/or LY294002 in 3T3-L1 Adipocytes. LIPIDS, v. 54, n. 2-3, p. 133-140, FEB-MAR 2019. Web of Science Citations: 3. (10/16911-4)
FONTES MORETTO, FERNANDA CRISTINA; DE SIBIO, MARIA TERESA; LUVIZON, ALINE CARBONERA; CASTRO OLIMPIO, REGIANE MARQUES; DE OLIVEIRA, MIRIANE; BARNABE ALVES, CARLOS AUGUSTO; CONDE, SANDRO JOSE; NOGUEIRA, CELIA REGINA. Triiodothyronine (T-3) induces HIF1A and TGFA expression in MCF7 cells by activating PI3K. Life Sciences, v. 154, p. 52-57, JUN 1 2016. Web of Science Citations: 3. (12/04684-9, 14/15209-5)
CAMPANHA, FABIO V. G.; PERONE, DENISE; DE CAMPOS, DIJON H. S.; LUVIZOTTO, RENATA DE A. M.; DE SIBIO, MARIA T.; DE OLIVEIRA, MIRIANE; OLIMPIO, REGIANE M. C.; MORETTO, FERNANDA C. F.; PADOVANI, CARLOS R.; MAZETO, GLAUCIA M. F. S.; et al. Thyroxine increases Serca2 and Ryr2 gene expression in heart failure rats with euthyroid sick syndrome. ARCHIVES OF ENDOCRINOLOGY METABOLISM, v. 60, n. 6, p. 582-586, NOV-DEC 2016. Web of Science Citations: 0.
DE SIBIO, MARIA TERESA; MELO LUVIZOTTO, RENATA AZEVEDO; CASTRO OLIMPIO, REGIANE MARQUES; CORREA, CAMILA RENATA; MARINO, JULIANA; DE OLIVEIRA, MIRIANE; CONDE, SANDRO JOSE; DOS ANJOS FERREIRA, ANA LUCIA; PADOVANI, CARLOS ROBERTO; NOGUEIRA, CELIA REGINA. A Comparative Genotoxicity Study of a Supraphysiological Dose of Triiodothyronine (T-3) in Obese Rats Subjected to Either Calorie-Restricted Diet or Hyperthyroidism. PLoS One, v. 8, n. 2, FEB 28 2013. Web of Science Citations: 10.
LUVIZOTTO, RENATA A. M.; NASCIMENTO, ANDRE F.; VEERAMACHANENI, SUDIPTA; LIU, CHUN; WANG, XIANG-DONG. Chronic Alcohol Intake Upregulates Hepatic Expression of Carotenoid Cleavage Enzymes and PPAR in Rats. Journal of Nutrition, v. 140, n. 10, p. 1808-1814, OCT 2010. Web of Science Citations: 13.
CONDE, S. J.; LUVIZOTTO, R. A. M.; SIBIO, M. T.; KATAYAMA, M. L. H.; BRENTANI, M. M.; NOGUEIRA, C. R.. Tamoxifen inhibits transforming growth factor-alpha gene expression in human breast carcinoma samples treated with triiodothyronine. Journal of Endocrinological Investigation, v. 31, n. 12, p. 1047-1051, DEC 2008. Web of Science Citations: 13.
DE OLIVEIRA, MIRIANE; MATHIAS, LUCAS SOLLA; RODRIGUES, BRUNA MORETTO; MARIANI, BIANCA GONCALVES; GRACELI, JONES BERNARDES; DE SIBIO, MARIA TERESA; CASTRO OLIMPIO, REGIANE MARQUES; FONTES MORETTO, FERNANDA CRISTINA; DEPRA, IGOR CARVALHO; NOGUEIRA, CELIA REGINA. The roles of triiodothyronine and irisin in improving the lipid profile and directing the browning of human adipose subcutaneous cells. Molecular and Cellular Endocrinology, v. 506, APR 15 2020. Web of Science Citations: 0. (16/03242-3)
CONDE, SANDRO JOSE; MELO LUVIZOTTO, RENATA DE AZEVEDO; DE SIBIO, MARIA TERESA; NOGUEIRA, CELIA REGINA. Human breast tumor slices as an alternative approach to cell lines to individualize research for each patient. European Journal of Cancer Prevention, v. 21, n. 4, p. 333-335, JUL 2012. Web of Science Citations: 4.
MELO LUVIZOTTO, RENATA DE AZEVEDO; DO NASCIMENTO, ANDRE FERREIRA; DE SIBIO, MARIA TERESA; CASTRO OLIMPIO, REGIANE MARQUES; CONDE, SANDRO JOSE; LIMA-LEOPOLDO, ANA PAULA; LEOPOLDO, ANDRE SOARES; CICOGNA, ANTONIO CARLOS; NOGUEIRA, CELIA REGINA. Experimental Hyperthyroidism Decreases Gene Expression and Serum Levels of Adipokines in Obesity. SCIENTIFIC WORLD JOURNAL, 2012. Web of Science Citations: 3.
PERONE, D.; TEIXEIRA, S. S.; CLARA, S. A.; SANTOS, D. C. DOS; NOGUEIRA, C. R.. Aspectos genéticos do hipotireoidismo congênito. Arquivos Brasileiros de Endocrinologia e Metabologia, v. 48, n. 1, p. 62-69, fev. 2004. (99/03570-3)
BAUAB‚ RCM; PERONE‚ D.; CASTRO‚ AVB; CICOGNA‚ AC; NOGUEIRA‚ CR. Low triiodothyronine (T3) or reverse triiodothyronine (rT3) syndrome modifies gene expression in rats with congestive heart failure. ENDOCRINE RESEARCH, v. 31, n. 4, p. 397-405, 2005.
PATRÍCIA P. SARAIVA; SILVANIA S. TEIXEIRA; CÉLIA REGINA NOGUEIRA; CARLOS ROBERTO PADOVANI. Triiodothyronine (T3) does not induce Rankl expression in rat Ros 17/2.8 cells. Arquivos Brasileiros de Endocrinologia e Metabologia, v. 52, n. 1, p. 109-113, Fev. 2008.
FIGUEIREDO, NANCY BUENO; CESTARI, SILVIA HELENA; CONDE, SANDRO JOSE; MELO LUVIZOTTO, RENATA AZEVEDO; DE SIBIO, MARIA TERESA; PERONE, DENISE; HIRATA KATAYAMA, MARIA LUCIA; CARRARO, DIRCE MARIA; BRENTANI, HELENA PAULA; BRENTANI, MARIA MITZI; et al. Estrogen-Responsive Genes Overlap with Triiodothyronine-Responsive Genes in a Breast Carcinoma Cell Line. SCIENTIFIC WORLD JOURNAL, 2014. Web of Science Citations: 4.
SILVA, TABATA M.; MORETTO, FERNANDA C. F.; DE SIBIO, MARIA T.; GONCALVES, BIANCA M.; OLIVEIRA, MIRIANE; OLIMPIO, REGIANE M. C.; OLIVEIRA, DIEGO A. M.; COSTA, SARAH M. B.; DEPRA, IGOR C.; NAMBA, VICKELINE; et al. Triiodothyronine (T-3) upregulates the expression of proto-oncogene TGFA independent of MAPK/ERK pathway activation in the human breast adenocarcinoma cell line, MCF7. ARCHIVES OF ENDOCRINOLOGY METABOLISM, v. 63, n. 2, p. 142-147, MAR-APR 2019. Web of Science Citations: 1. (15/09686-8, 14/15209-5, 13/05629-4)
LUVIZOTTO, R. A. M.; SIBIO, M. T.; OLIMPIO, R. M. C.; NASCIMENTO, A. F.; LIMA-LEOPOLDO, A. P.; LEOPOLDO, A. S.; PADOVANI, C. R.; CICOGNA, A. C.; NOGUEIRA, C. R.. Supraphysiological Triiodothyronine Doses Diminish Leptin and Adiponectin Gene Expression, but do not Alter Resistin Expression in Calorie Restricted Obese Rats. Hormone and Metabolic Research, v. 43, n. 7, p. 452-457, JUN 2011. Web of Science Citations: 9.
FÁBIO V. G. CAMPANHA; DENISE PERONE; DIJON H. S. DE CAMPOS; RENATA DE A. M. LUVIZOTTO; MARIA T. DE SÍBIO; MIRIANE DE OLIVEIRA; REGIANE M. C. OLIMPIO; FERNANDA C. F. MORETTO; CARLOS R. PADOVANI; GLÁUCIA M. F. S. MAZETO; et al. Thyroxine increases Serca2 and Ryr2 gene expression in heart failure rats with euthyroid sick syndrome. ARCHIVES OF ENDOCRINOLOGY METABOLISM, n. ahead, p. 0-0, 2016.
MATHIAS, LUCAS SOLLA; RODRIGUES, BRUNA MORETTO; GONCALVES, BIANCA MARIANI; FONTES MORETTO, FERNANDA CRISTINA; CASTRO OLIMPIO, REGIANE MARQUES; DEPRA, IGOR; DE SIBIO, MARIA TERESA; TILLI, HELENA PAIM; NOGUEIRA, CELIA REGINA; DE OLIVEIRA, MIRIANE. Triiodothyronine activated extranuclear pathways upregulate adiponectin and leptin in murine adipocytes. Molecular and Cellular Endocrinology, v. 503, MAR 1 2020. Web of Science Citations: 0. (10/16911-4)
(References retrieved automatically from State of São Paulo Research Institutions)
RODRIGUES, Bruna Moretto. Avaliação da ação do hormônio tireoidiano na expressão dos RNAs codificantes em células osteoblásticas derivadas do tecido adiposo humano.. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Medicina. (15/26747-0)
CONDE, Sandro José. Inter-relação da modulação gênica entre triidotironina(T3) e estradiol(E2) em cultura primária de adenocarcinoma de mama. 88 f. Tese (Doutorado) - Campus de Botucatu. Universidade Estadual Paulista (UNESP). Botucatu. (05/55459-1)
COSTA, Sarah Maria Barneze. Efeito do estrógeno (E2) e da Triiodotironina (T3) na síntese proteica de RANKL e TNF-α em células osteoblásticas derivadas do tecido adiposo. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Medicina. (14/15529-0)
MARINO, Juliana. Efeito de diferentes doses de hormônios tireoidianos sobre a expressão gênica e protéica de proteínas relacionadas ao trânsito de cálcio em animais obesos e obesos submetidos à restrição alimentar. 105 f. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Medicina. Botucatu. (08/56330-0)
FIGUEIREDO, Nancy Bueno. Inter-relação entre a modulação gênica da triidotironina(T3) e do estradiol(E2) em adenocarcinoma de mama. 134 f. Tese (Doutorado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Medicina. Botucatu. (02/09481-7)
SIBIO, Maria Teresa de. Ação do hormônio triodotironina (T3) altera a expressão gênica do oncogene Amphiregulin (Areg) el células tumorais de adenocarcinoma de mama. 47 f. Tese (Doutorado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Medicina. (09/15607-2)