Abstract
Duodenal ulcer-promoting gene A (dupA), is a novel virulence factor, in Helicobacter pylori and was associated with duodenal ulcer development and reduced risk for gastric carcinoma in some populations. In additional, E-caderin gene seems to be associated with infiltrative and metastatic ability of gastric tumors. Previous studies suggesting that gene inactivation of E-cadherin by H. pylo…