- Research Grants
Researcher at the Structural Genomic Consortium (SGC-UNICAMP) since January 2018, acting as a medicinal chemist in the design and synthesis of protein kinases inhibitors. Graduated from Catholic University of Santos (2010), during the graduation period was a student of scientific initiation at the Center for Training and Research in the Environment (CEPEMA-USP) (2009-2011). Obtained his Master´s degree (2013) and PhD (2017) from the Faculty of Pharmaceutical Sciences of the University of São Paulo (FCF-USP) under the supervision of Professor Dr. Helio A. Stefani. During the master's held sandwich internship at the University of Massachusetts, Boston (UMASS-Boston) under the supervision of Professor Dr. Wei Zhang. As post-doc started a collaboration between SGC-Unicamp and the Andrei Yudin lab at the University of Toronto to develop new methods for efficient protein kinases inhibitors based on boron chemistry (Source: Lattes Curriculum)
Protein kinases are the enzyme family involved in the control and modulation of a wide range of biological process. Their catalytic activity comprises the transfer of a phosphate group from adenosine triphosphate (ATP) to protein substrates containing tyrosine, serine and/or threonine amino acid residues. In order to understand the function of each of the ~500 kinases and their effect o...
The project aims at the synthesis and functionalization of derivatives (L)-tyrosine from the reaction of potassium organotrifluoroborate salts and 3-iodo-(L)-tyrosine and biological evaluation of the synthesized products.
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|