CV Lattes
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Universidade de São Paulo (USP). Faculdade de Zootecnia e Engenharia de Alimentos (FZEA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Researcher at the Van Andel Institute, MI-USA, working in the field of neuroscience with a focus on cell reprogramming and cell differentiation into neurons. She was a post-doctoral student at the University of São Paulo with a study on the generation of induced pluripotent cells (iPSCs) and primordial germ cells. She participated in the Internship Research Abroad Program (BEPE), working for one year under Professor Dr. W. Allan King's supervision at the University of Guelph, Guelph-ON, Canada. Ph.D. at the University of São Paulo - USP - in the postgraduate program of the Anatomy of Domestic and Wild Animals at the Faculty of Veterinary Medicine and Animal Science (FMVZ), in the field of germ cells and epigenetic modifications, under Professor Dr. Daniele dos Santos Martins's supervision. She participated in the Research Internship Abroad (BEPE) program, working for ten months under the direction of Professor Dr. Susana Chuva Sousa Lopes at Leiden University Medical Centrum, Leiden-Netherlands. (Source: Lattes Curriculum)
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The embryonic development period is marked by important epigenetic processes including mechanisms of sex determination and X chromosome reprogramming. X-chromosome inactivation (XCI) is an important epigenetic marker for proper embryonic and fetal development, whereas X-chromosome reactivation (XCR) influences the pluripotent state of the cells, and thus, it is an important epigenetic mod…
The epigenetic reprogramation is crucial for genome regulation during the development of germ cells, which are responsible for originating the gametogenic lineage in mammals. The demethylation in primordial germ cells is a unique key event to erase the epigenetic memory and prevent epimutations transmissions in the next generation. There is limited information on how these events are cons…
Induced pluripotent stem cells (iPSCs) obtained from different tissues allow us to generate relevant cell types that enable the formation or repair of damaged tissue and the generation of new in vitro models of syndromes or diseases. Moreover, human embryonic stem cells (hESCs) and iPSCs have recently been used to induced primordial germ cells like (PGCs-like), making then of great intere…
Germ cells are responsible for transmitting genetic material to the next generation. The defects of formation during development may cause infertility problems in both, men and women. Several studies in animals and humans have demonstrated that it is possible to culture and differentiate of germ cells in vitro. The use of primordial germ cells (PGCs) for embryonic germ cells (EGCs) deriva…
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