CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Current PhD student in Neuroscience with a focus on Immunopsychiatry, MSc completed in 2019 in the same area of research at the Department of Neuroscience and Behaviour - Ribeirão Preto Medical School, University of São Paulo - Brazil. Short term MSc student in 2018 at the Institute of Psychiatry, Psychology and Neuroscience, King's College London (IoPPN - KCL) - Stress, Psychiatry and Immunology Laboratory. Interested in the association between the immune system and the central nervous system in the context of psychotic disorders. (Source: Lattes Curriculum)
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According to theories of a psychosis continuum, Psychotic-Like Experiences (PLEs) are present in a significant proportion of the general population, increasing in 5 to 16 times the future risk of transiting toward a schizophrenia-spectrum disorder. Growing body of evidence suggests a role of the immune system in psychosis; hitherto, little is known about alterations of inflammatory marker…
Gene-environment interaction (GxE) is being target as a novel avenue of exploration in the understanding of psychotic disorders (PD). Notably, childhood adversity (CA) is considered an important environmental risk factor in this context. Recently, the inflammatory hypothesis is being considered in the development of PD, with special attention to the participation of the cytokines IL-6, TN…
Existing theories regarding the cause of depressive disorders focus on monoamines, specially the role of serotonin (5-HT). Evidences support the hypothesis that serotoninergic neurotransmission is not only involved with the process of adaptation to aversive events, but it is also sensible to different kinds of stressors. The literature provides evidence that the serotonin pathway connecti…
Background. We and others have identified signs of immune dysregulation in patients with psychosis relative to community-based controls. Interleukin (IL)-6 stands out as the most consistently raised cytokine in the liquor and blood of patients, including evidence in drug-naïve patients. Although adjunctive anti-inflammatory treatments in psychosis are promising, these have yielded mixed r…
Epidemiological studies strongly suggest an association between childhood maltreatment and psychosis, and that the cessation of traumatic experiences may reduce the incidence of psychosis by 33%. Recent investigations started to suggest inflammatory cytokine dysfunction in psychosis, and that childhood adversity may underlie this relationship. Despite of that, only two clinical studies ha…
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