Abstract
The drugs Sildenafil and Simvastatin modulate the activity of proteins and molecules involved in intracellular signaling. Simvastatin is a molecule of the statins family, which are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase. In addition to this function, it's also currently assigned to Simvastatin via an inhibitory effect on the GTPase Rho (family of proteins that inclu…