Abstract
HPV-16 and HPV-18 are strongly associated with risk of developing cervical cancer. Worldwide, HPV-16 type is the most prevalent type in invasive squamous cell carcinomas of the cervix, followed by HPV-18, whereas HPV-18 is the most prevalent type in adenocarcinoma specimens. HPV-18 intratypic nucleotide variability has been studied resulting in important findings concerning the evolution …