- Research Grants
graduation at Licenciatura Plena from Universidade Presbiteriana Mackenzie (2008), graduation at Ciências Biológicas from Universidade Presbiteriana Mackenzie (2009), master's at Ciências (Toxinologia) from Instituto Butantan (2012) and doctorate at Immunology from Universidade de São Paulo (2017). Has experience in Morphology, focusing on Morphology, acting on the following subjects: serpente, ultraestrutura, glandula de veneno, histopatologia and veneno. (Source: Lattes Curriculum)
Crotoxin (CTX) is a neurotoxin isolated from Crotalus durissus terrificus snake venom that exhibits anti-inflammatory, immunomodulatory and antitumor activities. In this sense, many studies have demonstrated that CTX exerts a striking antitumor effect in several types of tumor, such as cutaneous melanoma, a disease without cure. On the other hand, recently, our group has demonstrated th...
Bothrops snake venoms contain high concentrations of secreted Phospholipases A2 (sPLA2). These enzymes present high grade of homology with mammalian group IIA-PLA2, which levels are marked increased during inflammatory diseases such as aterosclerosis. MT-III, is a GII-A Asp49-sFLA2 isolated from Bothrops asper venom. Besides myotoxicity, this enzyme induces a pronounced inflammatory rea...
Phospholipases A2 (PLA2s) are abundant in snake venoms and have been widely employed as pharmacological tools to investigate the role of this class of enzymes in diverse pathophysiological processes. MT-III, an Asp49 PLA2 isolated from Bothrops asper snake venom is classified into the group IIA sPLA2s. Mammalian GIIA-PLA2s are highly expressed in vascular smooth muscle cells (VSMCs) and...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|