CV Lattes
Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Licenciatura Plena from Universidade Presbiteriana Mackenzie (2008), graduation at Ciências Biológicas from Universidade Presbiteriana Mackenzie (2009), master's at Ciências (Toxinologia) from Instituto Butantan (2012) and doctorate at Immunology from Universidade de São Paulo (2017). Has experience in Morphology, focusing on Morphology, acting on the following subjects: serpente, ultraestrutura, glandula de veneno, histopatologia and veneno. (Source: Lattes Curriculum)
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Crotoxin (CTX) is a neurotoxin isolated from Crotalus durissus terrificus snake venom that exhibits anti-inflammatory, immunomodulatory and antitumor activities. In this sense, many studies have demonstrated that CTX exerts a striking antitumor effect in several types of tumor, such as cutaneous melanoma, a disease without cure. On the other hand, recently, our group has demonstrated that…
Bothrops snake venoms contain high concentrations of secreted Phospholipases A2 (sPLA2). These enzymes present high grade of homology with mammalian group IIA-PLA2, which levels are marked increased during inflammatory diseases such as aterosclerosis. MT-III, is a GII-A Asp49-sFLA2 isolated from Bothrops asper venom. Besides myotoxicity, this enzyme induces a pronounced inflammatory react…
Phospholipases A2 (PLA2s) are abundant in snake venoms and have been widely employed as pharmacological tools to investigate the role of this class of enzymes in diverse pathophysiological processes. MT-III, an Asp49 PLA2 isolated from Bothrops asper snake venom is classified into the group IIA sPLA2s. Mammalian GIIA-PLA2s are highly expressed in vascular smooth muscle cells (VSMCs) and t…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
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