Abstract
Galanin, originally assigned as neuropeptide, has been associated in several physiologic and pathologic processes, being its activity regulated by GALR1, GALR2 and GALR3 receptors. Specifically, GALR2 exhibits pro-tumoral property in head and neck squamous cells carcinoma (HNSCC) and is the only one among the others expressed in peripheral mononuclear cells. In rodents, HNSSC cells invasi…