Karina Bezerra Salomão Xavier
CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Universidade Estadual de Maringá (2010), master's at Genetics from Universidade de São Paulo (2013) and doctorate at Genetics from Universidade de São Paulo (2017). Has experience in Genetics, focusing on Genetics, acting on the following subjects: medulloblastoma, wnt signaling pathway, tet gene, 5-hydroxymethylcytosine and tet genes. (Source: Lattes Curriculum)
- "demethylation of specific tumor suppressor in medulloblastoma using dCas9-Tet1 system", BP.PD
Abstract
Medulloblastoma is the most commom tumor in the childhood. This tumor originates from cerebellum, and it is classified as an embryonic tumor. Biology of MB is intrinsically associated with deregulation of signaling pathways that control embryonic development of cerebellum. Therefore, the identification of alterations in molecular mechanisms could result in less toxicity and decrease of ...
- Study of TET gene expression and hydroxymethylation levels in medulloblastoma, BP.DR
Abstract
Medulloblastoma (MB) originates in the cerebellum and represents the most common malignant brain tumor in childhood. The MB is traditionally divided into five histologic groups related to prognosis: MB desmoplastic, nodular, classic, anaplastic or anaplastic large cell. In recent years, gene expression studies of MB allowed the classification of the tumor into four subgroups: (1) WNT, (...
- Epigenetic regulation of retroelements by TET enzymes in neural precursor cells, BE.EP.DR
Abstract
Long interspersed nuclear elements (LINE-1 or L1) are classified as non-long terminal repeat (LTR) retroelements, which have the ability to replicate and reintegrate in the host genome. In neuronal precursor cells (NPCs), L1s are expressed and mobile. Somatic L1 insertions have been detected in protein-coding and tissue-specific genes. L1s therefore generate genetic somatic mosaicism in...
| 1 / 1 | Ongoing scholarships in Brazil |
| 1 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 3 | All Scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SALOMAO, KARINA BEZERRA; VEIGA CRUZEIRO, GUSTAVO ALENCASTRO; BONFIM-SILVA, RICARDO; GERON, LENISA; RAMALHO, FERNANDO; SAGGIORO, FABIANO PINTO; SERAFINI, LUCIANO NEDER; ANTUNES MORENO, DANIEL; DE PAULA QUEIROZ, ROSANE GOMES; AGUIAR, SIMONE DOS SANTOS; et al. Reduced hydroxymethylation characterizes medulloblastoma while TET and IDH genes are differentially expressed within molecular subgroups. JOURNAL OF NEURO-ONCOLOGY, v. 139, n. 1, p. 33-42, AUG 2018. Web of Science Citations: 0. (13/15125-3, 14/20341-0)
(References retrieved automatically from State of São Paulo Research Institutions)
XAVIER, Karina Bezerra Salomão. Estudo da expressão dos genes TETs e níveis de hidroximetilação em meduloblastoma. 2017. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (13/15125-3)