CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Biomedicina from Universidade Estadual de Londrina (2012), master's at Biochemistry from Universidade Estadual de Campinas (2015) and doctorate at Biochemistry from Universidade Estadual de Campinas (2017). Has experience in Physiology, focusing on Endocrinal Physiology, acting on the following subjects: doenças autoimunes, artrite reumatoide, lúpus eritematoso sistêmico and htlv-1. (Source: Lattes Curriculum)
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PPAR³ agonists increase the insulin sensitivity and are used in the treatment of type 2 diabetes mellitus (T2DM). In pancreatic islets, PPAR³ controls insulin secretion, oxidative stress, SR stress and amyloid formation. It is known that the insulin-degrading enzyme (IDE) is the main responsible for the degradation of islet amyloid polypeptide (IAPP), reducing the amyloid formation. Based…
PPAR³ agonists increase the insulin sensitivity and are used in the treatment of DM2. In pancreatic islets, PPAR³ controls: insulin secretion, oxidative stress, SR stress, and amiloid formation. It is known that the insulin degrading enzyme (IDE) is the (main) responsible for the degradation of IAPP, reducing the amiloid formation. Based on the fact that PPAR³ increases the expression of …
Obesity is a public health problem. Obese individuals are more prone to developing chronic diseases such as Hypertension, Arteriosclerosis and Diabetes Mellitus type 2 (DM2). High-fatty diet is a robust model for the study of obesity and physical exercise is recommended for the treatment and prevention of this pathology. The acute exercise increase the plasmatic concentrations of interleu…
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