CV Lattes
ResearcherID
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Currently a visiting PhD student at Karolinska Institutet, Sweden, under the supervision of prof. Volker M. Lauschke. PhD candidate at the Pharmacy (Pathophysiology and Toxicology) postgraduate program at the School of Pharmaceutical Sciences in the University of Sao Paulo (FCF-USP), with FAPESP grant, started in Dec/2016. Graduated in Pharmacy-Biochemistry at the University of Sao Paulo (2009-2015), with training in Pharmacovigilance at the School of Pharmaceutical Sciences of the Sao Paulo State University Julio de Mesquita Filho (FCF-UNESP) from Mar/2016 to Aug/2016. I have concluded two research projects: the first in Molecular Biology under the supervision of Prof. Aline Maria da Silva, Ph.D. (IQ-USP) (2010-2011) and the second in Pharmacovigilance under the supervision of Prof. Nicolina Silvana Romano Lieber (FSP-USP) (2014-2015). I also studied at the Universidad Autónoma de Madrid (Madrid, 2012) with a scholarship provided by Santander bank. (Source: Lattes Curriculum)
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Familial Hypercholesterolemia (FH) is a primary dyslipidemia with frequent monogenic inheritance resulting from functional mutations in the Low Density Lipoprotein Receptor (LDLR), apolipoprotein B (APOB) and Proprotein convertase subtilisin/kexin type 9 (PCSK9) genes, which codify proteins that regulate cholesterol homeostasis. The first-line treatment consists of the use of statins, suc…
Chart review using triggers has been considered one of the most efficient methods for adverse drug events (ADE) detection. Recently, a list of pediatric-specific triggers has been developed. However, there still are few studies using this tool, especially with children hospitalized in Pediatric Intensive Care Unit (PICU), which are more likely to have ADE. Therefore, it is necessary to st…
Familial hypercholesterolemia (FH) is a primary dyslipidemia resulting from functional mutations in cholesterol homeostasis genes. Statins are the first-line treatment, but the response is highly variable among individuals. Pharmacogenetic scores have been developed to predict this variability, but none is specific to the Brazilian FH population. Also, the impact of variants found on prod…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
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(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 2 |
| Citations | 0 |
| Cit./Article | 0.0 |
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ZHOU, YITIAN; DAGLI HERNANDEZ, CAROLINA; LAUSCHKE, VOLKER M.. Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier. BRITISH JOURNAL OF CANCER, v. 123, n. 12, p. 1782-1789, DEC 8 2020. Web of Science Citations: 0. (19/19009-4)
DAGLI-HERNANDEZ, CAROLINA; COSTA DE FREITAS, RENATA CAROLINE; RODRIGUES MARCAL, ELISANGELA DA SILVA; GONCALVES, RODRIGO MARQUES; FALUDI, ANDRE ARPAD; BORGES, JESSICA BASSANI; BASTOS, GISELE MEDEIROS; LOS, BRUNA; MORI, AUGUSTO AKIRA; BORTOLIN, RAUL HERNANDES; et al. Late response to rosuvastatin and statin-related myalgia due to SLCO1B1, SLCO1B3, ABCB11, and CYP3A5 variants in a patient with Familial Hypercholesterolemia: a case report. ANNALS OF TRANSLATIONAL MEDICINE, v. 9, n. 1, JAN 2021. Web of Science Citations: 0. (16/25637-0, 16/12899-6)