- Research Grants
graduation at Ciências Biológicas: Modalidade Médica from Universidade Federal do Rio de Janeiro (2014) and master's at Biochemistry from Universidade Federal de São Paulo (2016). (Source: Lattes Curriculum)
Aging increases the risk of chronic diseases, being slowed by caloric restriction. Our group and coworkers identified that, in a conserved way, the synthesis of microRNAs decrease with aging, being reverted by caloric restriction. This phenomenon is a consequence of the regulation of the expression of key enzymes of the microRNA processing pathway, particularly Dicer, which cleaves pre-...
C. elegans is a widely used model for aging studies due to its short lifespan and conserved genes that can be easily silenced by feeding worms with bacteria that express target-specific double stranded RNA (dsRNA). Worms carrying a loss-of-function mutation in the glp-1 gene do not develop the germline and therefore are long-lived - a phenomenon directly linked to increased nuclear loca...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|