Abstract
The silicate-based cements have earned highlight. For this purpose, human osteoblast-like cells SAOS-2 (ATCC HTB-85) are used for analysis of cell cytotoxicity by MTT assay and bioactivity by the enzyme alkaline phosphatase activity and the presence of calcium deposits by alizarin red stain. Moreover, the tissue reaction caused by different materials in subcutaneous of sixty rat will be e…