CV Lattes
Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Pharmaceutical Sciences from the University of Ribeirão Preto - UNAERP (2008-2011), MSc in Biosciences and Biotechnology applied to Pharmacy by Universidade Estadual Paulista - UNESP (2012-2014) and PhD in Pharmaceutical Sciences with the same University, with Sandwich period at the Venetian Institute of Molecular Medicine at the University of Padova (Italy). I have experience in the field of biochemistry and enzymology (basic and clinical), Phytotherapy and Pharmacology, working in research on topics related to Diabetes Mellitus, Natural Products, Oxidative Stress, Muscular Atrophy and Phosphodiesterase Inhibitors. (Source: Lattes Curriculum)
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Increase in the intracellular levels of cyclic AMP (cAMP) is an essential event participating inthe inhibition of skeletal muscle protein degradation by catecholamines, after binding to beta 2-adrenoceptors. Two intracellular cAMP-dependent effectors seem to be involved in the antiproteolytic response of cAMP in the skeletal muscle: I) EPAC (Exchange protein directly activated by cAMP) th…
The knowledge of the mechanisms regulating skeletal muscle mass is of great relevance, since the excessive loss of muscle mass associated with various clinical conditions can lead to serious health complications. Considering the evidences for the role of cyclic adenosine 3,5-monophosphate (cAMP) signaling in the inhibition of muscle proteolysis by catecholamines and beta2-adrenergic agoni…
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