Abstract
Human papillomaviruses (HPV) are double-stranded DNA viruses that infect epithelial cells of skin and mucosa. Some HPV types, collectively known as high-risk types, are etiologically associated to almost all cervical tumors and more than 50% of other anogenital malignancies. Infection by these HPV types has been associated with genomic instability, a hallmark of most human malignancies. H…