Abstract
Streptococcus pneumoniae, or pneumococcus, is a component of the human microbiota, but in some cases it can cause diseases such as Sinusitis, Otitis Media, Pneumonia, Sepsis and Meningitis. Vaccination is the most effective strategy to control pneumococcal infections. The first generation pneumococcal vaccines are composed by free capsular polysaccharides (PS), inducing temporary protecti…